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Rapid Communications in Mass Spectrometry Journal

Papers
Rapid Communications in Mass SpectrometryVolume 21, Issue 18 p. 3165-3168 Letter to the Editor Differentiation of both linkage position and anomeric configuration in underivatized glucopyranosyl disaccharides by anion attachment with post-source decay in matrix-assisted laser des...
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RATIONALE:Isotope reference materials are essential to enable reliable and comparable isotope data across multiple laboratories. Although many reference materials already exist, the best reference materials should mimic the unknown samples, so new reference materials continue to ...
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A novel method has been developed for the rapid desalting of proteins and peptides for electrospray ionization mass spectrometry (ESI-MS). Protein and peptide solutions having high salt concentrations were infused into a microdialysis tube which was directly interfaced with a mic...
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Andrew C. Smith, Steve Welsh, Helen Atkinson, David Harris,Melanie J. Leng
RationaleThe dual isotope ratio analysis, carbon (δ13C value) and hydrogen (δ2H value), of methane (CH4) is a valuable tracer tool within a range of areas of scientific investigation, not least wetland ecology, microbiology, CH4 source identification and the tracing of geological...
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RATIONALE:Compound-specific stable carbon isotope analysis by gas chromatography/combustion/isotope ratio mass spectrometry (GC/C/IRMS) is widely used in studies of environmental or biological functioning. In the case of derivatized molecules, a calibration might be required due ...
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B(n)C clusters (n = 3-10) were studied at the density functional theory (DFT) (B3LYP)/6-311G** level of theory. The calculations predicted that the most stable configurations of the B(n) C clusters are the (n + 1)-membered cyclic structures. For boron-carbon clusters, the configu...
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The effect of nitrogen as the collision-activated dissociation (CAD) gas on the fragmentation of dipyridamole was investigated in the range of 10-90eV collision energy. The results support the collision model reported elsewhere, that the degree of ion fragmentation increases with...
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A method has been developed for the determination of the amino-acid sequence of a cyclic peptide containing cystine. It is based on the reduction of the peptide in a reductive matrix prior to ionization by fast-atom bombardment. The amino-acid sequence of the resulting linear pep...
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Rationale Organometallic compounds are becoming increasingly important in their industrial application as catalysts. Mass spectrometry is an essential tool for the structural confirmation of such organometallics. Because the analysis of this class of molecules can be challenging,...
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Rationale Pesticides are a group of micropollutants that persist for a long time in the environment and pose threats to life. Much effort has been devoted to developing pre-concentration methods capable of producing samples suitable for the detection of pesticides. However, bette...
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RATIONALE:Beta vulgaris L. has attracted increasing attention because of its broad application. The root of B. vulgaris L. (beetroot) possesses many excellent biological properties such as antianemic, anti-inflammatory, antihypertensive, antioxidant, anticarcinogenic, antipyretic...
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This paper describes the use of chemical reaction interface mass spectrometry (CRIMS) combined with liquid chromatography for the detection of trace level sulfur-containing impurities in pharmaceutical materials. A mixture of sulfur- and non-sulfur-containing compounds were analy...
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Liquid-liquid extraction of zirconium, one of the most important fission products, was followed using electrospray ionization mass spectrometry under conditions simulating reprocessing of nuclear spent fuel. Zr-IV can precipitate from the organic phase after extraction by dibutyl...
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RATIONALE Sodium dodecyl sulfate (SDS) is widely used for the solubilization and denaturation of proteins, but it interferes with liquid chromatography/mass spectrometry (LC/MS), suppressing protein signals or forming adduct ions. A quick and effective clean-up technique of SDS i...
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Nitrogen (N) cycling can be an important constraint on forest ecosystem response to elevated atmospheric CO(2). Our objective was to trace the movement of (15)N, injected into tree sap, to labile and stable forms of soil organic matter derived partly from the turnover of tree roo...
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Nanoelectrospray ionization (nESI) coupled online with high-field asymmetric waveform ion mobility spectrometry (FAIMS) for small molecule analysis in a discovery pharmaceutical setting was examined. A conventional capillary pump, autosampler and nESI source were used to introduc...
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RATIONALE A number of synthetic cathinones (aminoketones, 'bath salts') are tertiary amines containing a cyclic amino group, most commonly pyrrolidine. These totally synthetic compounds can be prepared in a number of regioisomeric designer modifications and many of these can yiel...
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RATIONALE An application of microdialysis sampling for evaluation of the interaction property of small molecules to macromolecules is presented. Microdialysis combined with liquid chromatography coupled to quadrupole time-of-flight tandem mass spectrometry (LC/QTOF-MS/MS) was est...
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The determination of isotope ratios of non-exchangeable hydrogen in tree-ring cellulose is commonly based on the nitration of wood cellulose followed by online high-temperature pyrolysis and isotope ratio mass spectrometry measurement of cellulose nitrate samples. The application...
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Ana Butorac, Meliha Solak Mekic,Amela Hozic,Janko Diminic, Dragan Gamberger,Marija Nisavic,Mario Cindric
RATIONALE: One of the most challenging tasks of proteomics is peptide de novo sequencing. 4-Sulfophenyl isothiocyanate (SPITC) peptide derivatization enables acquisition of high-quality tandem mass spectra (MS/MS) for de novo sequencing, but unwanted non-specific reactions and re...
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