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    • Anti-infection Pharmacy Journal

    Papers
    恩替卡韦对慢性乙型肝炎患者近期疗效的评价
    Wu-han ZHANG
    Anti-infection Pharmacy（2015）
    目的:评价恩替卡韦对慢性乙型肝炎(CHB)患者初治的近期疗效,为临床合理用药提供参考.方法:将68例CHB患者随机分为两组,每组34例,以接受拉米夫定治疗者为A组,以接受恩替卡韦治疗者为B组;评价两组患者治疗6周后ALT、AST、GGT及HBV-DNA含量改善情况,并对接受3月治疗后两组HBV-DNA转阴率作一对比.结果:治疗6周后B组患者ALT、AST、GGT及HBV-DNA含量显著优于A组(P＜0.05);B组患者治疗3月后HBV-DNA阳性率显著低于A组(P＜0.05).结论:恩替卡韦可有效地提高CHB患者的近期疗效.
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    扶正胶囊中人参皂苷Rg_1与Re及Rb_1的质量测定
    WU Yang,WU Yin-sheng
    Anti-infection Pharmacy（2010）
    目的:建立扶正胶囊中人参皂苷Rg1、Re、Rb1超高效液相色谱(UPLC)测定方法。方法:采用Acquity1UPLCBEHC18色谱柱(2.1mm×100mm,1.7μm),以乙腈-水为流动相进行梯度洗脱,流速0.5mL/min,检测波长203nm,柱温40℃。结果:扶正胶囊中人参皂苷Rg1、Re、Rb1在14min内完全分离;人参皂苷Rg1和人参皂苷Re分离度达2.0,人参皂苷Rg1、Re、Rb1峰理论板数均超过20000;经外标法计算,含人参皂苷Rg1、Re、Rb1质量分别为0.71mg/g,3.841mg/g,10.61mg/g。结论:本法简便、...
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    Progress on the Study of Hospital-acquired Pneumonia
    Manli Zhou
    Anti-infection Pharmacy（2009）
    The purpose is to investigate the progress in guidelines for the management of hospital-acquired pneumonia (HAP), epidemiology of causative organisms and the preventive and therapeutic effect of anti-infective drug. The most common pathogens were staphylococcus aureus and pseudom...
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