Ajit Johnson Nirmal - The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh;/Univ Edinburgh, The University of Edinburgh;Univ Edinburgh, The University of Edinburgh

基本信息

Career Trajectory

Bio

Development of experimental and computational approaches to systematically decipher regulatory circuits that underlie cancer development, metastasis, and resistance to treatment.

Research Interests

Papers共 42 篇Author StatisticsCo-AuthorSimilar Experts

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A Survey on Computational Pathology Foundation Models: Datasets, Adaptation Strategies, and Evaluation Tasks

Dong Li,Guihong Wan,Xintao Wu, Xinyu Wu,Ajit J. Nirmal,Christine G. Lian,Peter K. Sorger,Yevgeniy R. Semenov,Chen Zhao

CoRR (2025)

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1404 Unveiling the Spatial Landscape of Persistent Stable Metastatic Lesions in Patients Treated with Anti-Ctla-4 or Anti-CTLA-4 + Anti-PD-1 Therapy at Single-Cell Resolution

Yingxiao Shi,Zoltan Maliga,Ajit J Nirmal,Roxanne J Pelletier,Tuulia Vallius, Christine G Lian,Guihong Wan, Boshen Yan, Yiwen He, Brigette Kobs,Jihye Park, Amy Huang,Tyler Aprati,Elizabeth I Buchbinder,David Liu,Peter K Sorger

Regular and Young Investigator Award Abstracts (2024)

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Craters on the Melanoma Surface Facilitate Tumor-Immune Interactions and Demonstrate Pathologic Response to Checkpoint Blockade in Humans

Aya Ludin, Georgia L Stirtz, Asaf Tal,Ajit J Nirmal, Naomi Besson,Stephanie M Jones,Kathleen L Pfaff,Michael Manos,Sophia Liu,Irving Barrera, Qiyu Gong,Cecilia Pessoa Rodrigues,Aditi Sahu,Elizabeth Jerison,Joao V Alessi,Biagio Ricciuti,Douglas S Richardson,Jodi D Weiss, Hadley M Moreau, Meredith E Stanhope,Alexander B Afeyan, James Sefton, Wyatt D McCall, Emily Formato, Song Yang,Yi Zhou, David P Hoytema van Konijnenburg, Hannah L Cole,Miguel Cordova,Liang Deng,Milind Rajadhyaksha, Stephen R Quake,Mark M Awad,Fei Chen,Peter K Sorger,F Stephen Hodi,Scott J Rodig,George F Murphy,Leonard I Zon

bioRxiv the preprint server for biology (2024)

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CD8+T-cell Interplay with Myeloid Cells As Spatial Determinant of Chemotherapy Response in the Tumor Microenvironment of Metastatic High- Grade Serous Ovarian Cancer

Inga-Maria P. Launonen,Erdogan P. Erkan,Iga Niemiec, Ada Junquera Mencia,Angela Szabo,Fernando Perez,Essi Kahelin,Sampsa Hautaniemi,Jaana Oikkonen,Johanna Hynninen,Anni Virtanen,Tuulia Vallius,Ajit J. Nirmal,Peter Sorger,Anna Vaharautio,Anniina Farkkila

CANCER RESEARCH（2024）

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Spatial Multi-Omics Profiling of Tumor Cell Phenotypes in Primary Cutaneous Melanoma at Single-Cell Resolution

Tuulia Vallius,Edward Novikov,Ajit Nirmal Johnson,Shi Yingxiao, Roxanne Pelletier,Shishir Pant,Zoltan Maliga,Alyce Chen,Clarence Yapp,Sabrina Chan,Christine Lian,George F. Murphy,Sandro Santagata,Peter Sorger

CANCER RESEARCHno. 6 (2024)

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Multiplexed 3D Analysis of Immune States and Niches in Human Tissue

Clarence Yapp,Ajit J Nirmal,Felix Zhou,Zoltan Maliga,Juliann B Tefft,Paula Montero Llopis,George F Murphy,Christine G Lian,Gaudenz Danuser,Sandro Santagata,Peter K Sorger, Human Tumour Atlas Network

bioRxiv the preprint server for biology (2024)

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Abstract A080: CD8+T-cell Interplay with Myeloid Cells As Spatial Determinant of Chemotherapy Response in the Tumor Microenvironment of Metastatic High-Grade Serous Ovarian Cancer

Inga-Maria P. Launonen,Erdogan P. Erkan,Iga Niemiec, Ada Junquera Mencía,Angela Szabo,Fernando Perez,Essi Kahelin,Sampsa Hautaniemi,Jaana Oikkonen,Johanna Hynninen,Anni Virtanen,Tuulia Vallius,Ajit J. Nirmal,Peter Sorger,Anna Vähärautio,Anniina Färkkilä

Cancer Researchno. 5_Supplement_2 (2024)

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SCIMAP: A Python Toolkit for Integrated Spatial Analysis of Multiplexed Imaging Data

Ajit J Nirmal,Peter K Sorger

J Open Source Softwno. 97 (2024)

Cited3Views0WOSEIBibtex

Chemotherapy Induces Myeloid-Driven Spatially Confined T Cell Exhaustion in Ovarian Cancer

Inga-Maria Launonen,Iga Niemiec, Maria Hincapie-Otero,Erdogan Pekcan Erkan, Ada Junquera,Daria Afenteva,Matias M. Falco, Zhihan Liang,Matilda Salko, Foteini Chamchougia,Angela Szabo,Fernando Perez-Villatoro,Yilin Li,Giulia Micoli,Ashwini Nagaraj,Ulla-Maija Haltia,Essi Kahelin,Jaana Oikkonen,Johanna Hynninen,Anni Virtanen,Ajit J. Nirmal,Tuulia Vallius,Sampsa Hautaniemi,Peter K. Sorger,Anna Vaharautio,Anniina Farkkila

CANCER CELLno. 12 (2024)

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