Lightfoot has taught many courses while at Gillings, including Developing, Implementing, and Evaluating Public Health Solutions in the MPH Core, Foundations of Health Equity, Social Justice and Human Rights in the EQUITY concentration and a previous Foundations course in the Health Behavior department. Currently, she teaches a graduate seminar on CBPR and photovoice, as well as a core course in the pan-university Graduate Certificate in Participatory Research program. She has taught undergraduates through her leadership of the Honors Study Abroad Program in Cape Town, South Africa and will be teaching a new undergraduate course, Community Engagement and Assessment to Advance Health Equity and Social Justice, starting in spring 2023.