Aysegul Ozen - Chemical Engineering Department and Polymer Research Center, Bogazici University

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Papers共 35 篇Author StatisticsCo-AuthorSimilar Experts

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Supplementary Methods from the Pan-RAF–MEK Nondegrading Molecular Glue NST-628 is a Potent and Brain-Penetrant Inhibitor of the RAS–MAPK Pathway with Activity Across Diverse RAS- and RAF-Driven Cancers

Meagan B. Ryan,Bradley Quade, Natasha Schenk, Zhong Fang, Marshall Zingg, Steven E. Cohen, Brooke M. Swalm, Chun Li,Ayşegül Özen,Chaoyang Ye,Maria Stella Ritorto, Xin Huang,Arvin C. Dar,Yongxin Han,Klaus P. Hoeflich,Michael Hale,Margit Hagel

crossref（2024）

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Machine Learning ADME Models in Practice: Four Guidelines from a Successful Lead Optimization Case Study

Alexander S. Rich,Yvonne H. Chan,Benjamin Birnbaum, Kamran Haider, Joshua Haimson, Michael Hale, Yongxin Han, William Hickman,Klaus P. Hoeflich, Daniel Ortwine,Aysegul Ozen, David Belanger

ACS MEDICINAL CHEMISTRY LETTERS（2024）

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Supplementary Tables 2-5 from the Pan-RAF–MEK Nondegrading Molecular Glue NST-628 is a Potent and Brain-Penetrant Inhibitor of the RAS–MAPK Pathway with Activity Across Diverse RAS- and RAF-Driven Cancers

crossref（2024）

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Abstract ND10: NST-628 is a Novel, Potent, Fully Brain-Penetrant MAPK Pathway Molecular Glue That Inhibits RAS- and RAF-driven Cancers

Meagan B. Ryan,Bradley Quade, Natasha Schenk, Zhong Fang, Marshall Zingg, Steven E. Cohen, Chun Li, Brooke M. Swalm,Aysegul Ozen,Chaoyang Ye,Maria Stella Ritorto,Xin Huang,Arvin C. Dar,Yongxin Han,Michael Hale,Margit Hagel,Klaus P. Hoeflich

Cancer Researchno. 7_Supplement (2024)

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Supplementary Figures S1-S12 from the Pan-RAF–MEK Nondegrading Molecular Glue NST-628 is a Potent and Brain-Penetrant Inhibitor of the RAS–MAPK Pathway with Activity Across Diverse RAS- and RAF-Driven Cancers

crossref（2024）

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Supplementary Table 6 from the Pan-RAF–MEK Nondegrading Molecular Glue NST-628 is a Potent and Brain-Penetrant Inhibitor of the RAS–MAPK Pathway with Activity Across Diverse RAS- and RAF-Driven Cancers

crossref（2024）

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Data from the Pan-RAF–MEK Nondegrading Molecular Glue NST-628 is a Potent and Brain-Penetrant Inhibitor of the RAS–MAPK Pathway with Activity Across Diverse RAS- and RAF-Driven Cancers

Meagan B. Ryan,Bradley Quade, Natasha Schenk, Zhong Fang, Marshall Zingg, Steven E. Cohen, Brooke M. Swalm, Chun Li,Aysegul Ozen,Chaoyang Ye,Maria Stella Ritorto, Xin Huang,Arvin C. Dar,Yongxin Han,Klaus P. Hoeflich,Michael Hale,Margit Hagel

CANCER DISCOVERY（2024）

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NST-628 is a novel molecular glue that inhibits signaling and pathway reactivation in oncogenic RAS-MAPK cancers

Bradley Quade,Meagan Ryan, Brooke Swalm, Steven Cohen, Zhong Fang,Aysegul Ozen, Xin Huang,Arvin C. Dar,Yongxin Han,Klaus P. Hoeflich,Margit Hagel,Michael Hale

MOLECULAR CANCER THERAPEUTICSno. 12 (2023)

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Abstract A086: NST-628 is a Novel Molecular Glue That Inhibits Signaling and Pathway Reactivation in Oncogenic RAS-MAPK Cancers

Bradley Quade,Meagan Ryan, Brooke Swalm, Steven Cohen, Zhong Fang,Aysegul Ozen,Xin Huang,Arvin C Dar,Yongxin Han,Klaus P Hoeflich,Margit Hagel,Michael Hale

Molecular Cancer Therapeuticsno. 12_Supplement (2023)

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