His research interests are in signal processing, machine learning, artificial intelligence, neural engineering and robotics. He has published 6 books, 5 chapters, and over 300 papers in various journals and conference proceedings. Dr. Chen is an IEEE Senior Member and serves (or has served) as a Technical Committee Member of IEEE SPS Machine Learning for Signal Processing (MLSP), and a Technical Committee Member of IEEE CIS Cognitive and Developmental Systems (CDS), and an Associate Editor (or Editor Board Member) for several international journals including IEEE Transactions on Circuits and Systems for Video Technology (TCSVT), IEEE Transactions on Neural Networks and Learning Systems (TNNLS), IEEE Transactions on Cognitive and Developmental Systems (TCDS), Neural Networks, Journal of The Franklin Institute, and Entropy.