The central aim in my lab is to understand the genetic, biological, and evolutionary basis of metabolic and cardiovascular phenotypes in human populations. To build this understanding, the lab constructs computational and statistical tools grounded in principles of population biology and quantitative genetics. These tools are then applied to genetic data collected across thousands of whole human genomes.

My research has answered population genetic questions about recent demographic and selective events in human populations, and work to develop new statistics to identify selective pressures is ongoing. Recent work in the lab has focused on statistical models which capture variability in the rate of mutation in the human genome.