Dr. Buttgereit has expertise in the treatment of a wide variety of musculoskeletal and rheumatic diseases, including osteoporosis, osteoarthritis, rheumatoid arthritis, myositis, connective tissue diseases and different forms of vasculitis. He is internationally recognised for his work on mechanisms and clinical effects of glucocorticoids and on bioenergetics of immune functions. He has been principal investigator and site investigator in a variety of clinical studies on effects of anti-inflammatory and immunomodulatory agents in patients with rheumatic disease.