Claire O'Brien

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Research interests
Claire's main research interests are host-microbe interactions in the inflammatory bowel diseases; understanding how perturbations of the gut microbiota relate to health and disease in humans; and the genetics of Escherichia coli.

研究兴趣

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Transcriptomic Signatures of Host Immune Responses in Aphthous Ulcers, the Earliest Lesions of Crohn's Disease, Suggest That a Bacterial Invasive Challenge, Rather Than Global Dysbiosis, is the Initiating Factor

Phillip J Whiley,Ojas V A Dixit, Mukta Das Gupta,Hardip Patel, Guoyan Zhao,Susan J Connor,Kim M Summers,David A Hume,Paul Pavli,Claire L O'Brien

Immunology and cell biologyno. 5 (2025): 473-484

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High Fat Diet Drives Increased Dysbiosis in IBD Compared to Healthy Controls

S. Koentgen,F. Zhang, S. Khadka,C. O'Brien,M. Grimm, E. Allen-Vercoe, G. L. Hold

JOURNAL OF CROHNS & COLITIS (2025): i2409-i2409

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The Relationship Between CSF1R Signaling, Monocyte-Macrophage Differentiation, and Susceptibility to Inflammatory Bowel Disease

David A Hume,Kim M Summers,Claire O'Brien,Paul Pavli

Cellular and molecular gastroenterology and hepatologyno. 8 (2025): 101510-101510

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Multi-omic Modelling of Antibiotic Perturbed Faecal Microbial Communities Demonstrates Reduced Microbial Resilience in IBD

S. Koentgen,F. Zhang,C. O'Brien, M. Grimm, E. Allen-Vercoe, G. L. Hold

JOURNAL OF CROHNS & COLITIS（2025）

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Multiomic Modelling of Antibiotic Perturbed Faecal Microbial Communities Demonstrates Reduced Microbial Resilience in Inflammatory Bowel Disease

Sabrina Koentgen,Fan Zhang, Swisha Khadka, Xiaotao Jiang, Thisun Jayawardana,Emma Allen-Vercoe,Claire O'Brien,Georgina Hold

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY（2024）

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Reducing the Risk of Pre-eclampsia in Women with Polycystic Ovary Syndrome Using a Combination of Pregnancy Screening, Lifestyle, and Medical Management Strategies

Jim Parker,Claire Louise O'Brien, Christabelle Yeoh,Felice L. Gersh,Shaun Brennecke

Journal of Clinical Medicineno. 6 (2024): 1774-1774

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The Relationship Between Extreme Inter-Individual Variation in Macrophage Gene Expression and Genetic Susceptibility to Inflammatory Bowel Disease

Claire L. O’Brien,Kim M. Summers,Natalia M. Martin,Dylan Carter-Cusack,Yuanhao Yang, Rasel Barua,Ojas V. A. Dixit,David A. Hume,Paul Pavli

Human Genetics（2024）

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Diversity of Antimicrobial-Resistant Bacteria Isolated from Australian Chicken and Pork Meat

Ojas V. A. Dixit,Mahboobeh Behruznia, Aidan L. Preuss,Claire L. O'Brien

FRONTIERS IN MICROBIOLOGY（2024）

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Transcriptomic Signatures of Antibacterial Responses in the Earliest Lesions of Crohn's Disease

P. Whiley,K. Summers,P. Pavli, D. Hume,C. O'Brien

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2023): 110-111

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Comparative Genomics and Phenotypic Studies to Determine Site-Specificity of Escherichia Coli in the Lower Gastrointestinal Tract of Humans

Rasel Barua,Paul Pavli,David M. Gordon,Claire L. O'Brien

Gut microbes (2023)

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论文共 69 篇作者统计合作学者相似作者