Dr. Wykoff is passionate about translational research and clinical trial design, and serves as principal investigator for numerous national clinical trials. publishing over 160 peer-reviewed scientific articles and frequently speaks at national and international academic meetings. His research interests pertain to angiogenesis and retinal vascular diseases including age-related macular degeneration, diabetic retinopathy, and venous occlusive diseases, as well as vitreoretinal surgical topics such as retinal tears and retinal detachments, as well as macular surgery for macular holes and macular puckers. He is highly trained and skilled to perform a variety of surgical procedures, and also works with patients to hold off surgery as long as possible with conservative, nonsurgical treatment when possible.