Christophe Mulle is a research director (DRCE) at the CNRS. He's a cellular neurobiologist with expertise in glutamate receptors, electrophysiology of synaptic transmission and neuronal circuits. After being trained in the labs of Jean-Pierre Changeux at the Pasteur Institute and Steve Heinemann (Salk Institute, San Diego), he created a CNRS laboratory in Bordeaux (1995). His research focuses on the mechanisms underlying the plasticity of synaptic properties and neural circuits in the hippocampus, in the context of episodic-like memory encoding. Great efforts are made to implement these questions at an integrated level in the mouse by developing methods for interrogating the connectivity and function of local circuits in vivo in behavioural conditions. These studies address physiological mechanisms as well as synaptic dysfunction in the context of Alzheimer's disease. In parallel, he has engaged into a translational project targeting ectopic KARs aberrantly expressed in the hippocampus, in temporal lobe epilepsy, in close collaboration with Valérie Crépel (Inserm, Marseille). In 2016, he was elected member of the Academia Europeae. In 2014, he has received the Grand Prix Lamonica de Neurologie of the French Academy of Science.