My interest is in understanding how mental disorders relate to neurobiological systems. Major questions include: 'What biological attributes confer risk for particular types of psychological problems?' and 'What can be done to prevent dispositional liabilities from developing into clinical disorders?" Disorders of interest include psychopathy, impulse control ("externalizing") disorders, and anxiety and mood ("internalizing") disorders. My lab group has worked to develop a Neuro-Behavioral Trait model for linking clinical problems to neural systems. Traits within this model include threat sensitivity, reward sensitivity, inhibitory control, and affiliative capacity. Methods used in my research include psychophysiology, neuroimaging, psychometrics, quantitative modeling, and behavioral genetics. I have served as President of both the Society for Psychophysiological Research (2011-12) and the Society for Scientific Study of Psychopathy (2007-09), and I was recipient of a Lifetime Scientific Career Contribution Award from the latter society in 2013.