Cornelis E C A Hop - Department of Drug Metabolism and Pharmacokinetics, Genentech Inc.

基本信息

浏览量：12

职业迁徙

个人简介

暂无内容

研究兴趣

论文共 133 篇作者统计合作学者相似作者

按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选

Transporter Expressions As Part of Required Scaling Factor to Support in Vitro in Vivo Extrapolation for Blood-Brain Barrier Drug Permeability

Zubida M. Al-Majdoub,Jonathan Cheong, Kunihiko Mizuno, Janita Hogan,Tom De Bruyn, Anne Kanta, Jingjing Guo,Cornelis E.C.A. Hop, Mike Zientek,Aleksandra Galetin,Kayode Ogungbenro, Amin Rostami-Hodjegan,Jill Barber

European Journal of Pharmaceutical Sciencespp.107022, (2025)

引用0浏览0WOS引用

Using the Dynamic Well-Stirred Model to Extrapolate Hepatic Clearance of Organic Anion-Transporting Polypeptide Transporter Substrates Without Assuming Albumin-Mediated Hepatic Drug Uptake

Zhengyin Yan,Li Ma,Nicky Hwang,Julie Huang,Jane R. Kenny,Cornelis E. C. A. Hop

DRUG METABOLISM AND DISPOSITION（2024）

引用3浏览0WOS引用

Survey of Pharmaceutical Industry's Best Practices Around in Vitro Transporter Assessment and Implications for Drug Development: Considerations from the International Consortium for Innovation and Quality for Pharmaceutical Development Transporter Working Group

Drug Metabolism and Dispositionpp.DMD-001587, (2024)

引用1浏览0WOS引用

Artificial Intelligence for Quantitative Modeling in Drug Discovery and Development: an Innovation and Quality Consortium Perspective on Use Cases and Best Practices

Nadia Terranova,Didier Renard,Mohamed H. Shahin,Sujatha Menon,Youfang Cao,Cornelis E. C. A. Hop, Sean Hayes,Kumpal Madrasi,Sven Stodtmann,Thomas Tensfeldt,Pavan Vaddady, Nicholas Ellinwood,James Lu

CLINICAL PHARMACOLOGY & THERAPEUTICS（2024）

引用11浏览0WOS引用

Introducing the Dynamic Well-Stirred Model for Predicting Hepatic Clearance and Extraction Ratio

Zhengyin Yan,Li Ma,Pasquale Carione,Julie Huang,Nicky Hwang,Jane R. Kenny,Cornelis E. C. A. Hop

Journal of Pharmaceutical Sciencesno. 4 (2024): 1094-1112

引用4浏览0WOS引用

Tissue Distribution and Retention Drives Efficacy of Rapidly Clearing VHL-based PROTACs

Donglu Zhang,Bin Ma,Peter S. Dragovich, Li Ma, Shu Chen,Eugene C. Chen,Xiaofen Ye,Joyce Liu,Jennifer Pizzano,Elizabeth Bortolon,Emily Chan, Xing Zhang, Chen,Elizabeth S. Levy,Robert L. Yauch,S. Cyrus Khojasteh,Cornelis E. C. A. Hop

COMMUNICATIONS MEDICINEno. 1 (2024)

引用2浏览0WOSNATURE引用

New Methodology for Determining Plasma Protein Binding Kinetics Using an Enzyme Reporter Assay Coupling with High-Resolution Mass Spectrometry

Zhengyin Yan,Li Ma,Julie Huang,Pasquale Carione,Jane R. Kenny,Cornelis E. C. A. Hop,Matthew Wright

ANALYTICAL CHEMISTRY（2023）

引用10浏览0WOS引用

ADME Assays

S. Cyrus Khojasteh,Harvey Wong,Donglu Zhang,Cornelis E.C.A. Hop

Discovery DMPK Quick Guidepp.175-215, (2022)

引用0浏览0引用

Candidate Translational Characterization

S. Cyrus Khojasteh,Harvey Wong,Donglu Zhang,Cornelis E.C.A. Hop

Discovery DMPK Quick Guidepp.141-161, (2022)

引用0浏览0引用

Physiologically Based Pharmacokinetic Models Can Be Used to Predict the Unique Nonlinear Absorption Profiles of Vismodegib

Louis Lin,Matthew R. Wright,Cornelis E. C. A. Hop,Harvey Wong

Drug Metabolism and Disposition（2022）

引用4浏览0WOS引用

加载更多

作者统计

合作学者

合作机构

D-Core

合作者
学生
导师

暂无相似学者，你可以通过学者研究领域进行搜索筛选

数据免责声明

页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果，我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问，可以通过电子邮件方式联系我们：report@aminer.cn