Donna Mceachern - Department of Internal Medicine, University of Michigan

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论文共 139 篇作者统计合作学者相似作者

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STAT5 and STAT3 Balance Shapes Dendritic Cell Function and Tumour Immunity

Jiajia Zhou, Kole Tison,Haibin Zhou,Longchuan Bai, Ranjan Kumar Acharyya,Donna McEachern,Hoda Metwally,Yu Wang,Michael Pitter,Jae Eun Choi,Linda Vatan, Peng Liao, Jiali Yu,Heng Lin,Long Jiang,Shuang Wei, Xue Gao, Sara Grove,Abhijit Parolia, Marcin Cieslik,Ilona Kryczek, Michael D Green,Jian-Xin Lin,Arul M Chinnaiyan, Warren J Leonard,Shaomeng Wang,Weiping Zou

Nature (2025)

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MD-4251: A First-in-Class Oral MDM2 Degrader Inducing Complete Tumor Regression with Single-Dose Administration

Ranjan Kumar Acharyya, Liyue Huang,Angelo Aguilar,Biao Hu,Longchuan Bai,Hoda Metwally,Donna McEachern,Wei Jiang, Yu Wang,Qiuxia Li,Bo Wen,Duxin Sun,Shaomeng Wang

Journal of medicinal chemistry (2025)

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Discovery of CW-3308 As a Potent, Selective, and Orally Efficacious PROTAC Degrader of BRD9

Changwei Wang,Mi Wang,Yu Wang,Rohan Kalyan Rej,Angelo Aguilar,Tianfeng Xu,Longchuan Bai,Jelena Tosovic,Donna McEachern,Qiuxia Li, Farzad Sarkari,Bo Wen,Duxin Sun,Shaomeng Wang

JOURNAL OF MEDICINAL CHEMISTRYno. 16 (2024): 14125-14154

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Discovery of CBPD-409 and CBPD-268 As Highly Potent and Orally Efficacious CBP/p300 PROTAC Degraders for the Treatment of Castration-Resistant Prostate Cancer

Zhixiang Chen,Mi Wang,Dimin Wu,Lijie Zhao,Tianfeng Xu,Hoda Metwally,Yu Wang,Donna McEachern,Wei Jiang,Longchuan Bai,Jie Luo,Meilin Wang,Ruiting Li,John Takyi-Williams,Lu Wang,Qiuxia Li,Bo Wen,Duxin Sun,Arul M. Chinnaiyan,Shaomeng Wang

Cancer Researchno. 6_Supplement (2024): 4504-4504

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Discovery of CBPD-268 As an Exceptionally Potent and Orally Efficacious CBP/p300 PROTAC Degrader Capable of Achieving Tumor Regression

Zhixiang Chen,Mi Wang,Dimin Wu,Longchuan Bai,Tianfeng Xu,Hoda Metwally,Yu Wang,Donna Mceachern,Lijie Zhao,Ruiting Li,John Takyi-Williams,Meilin Wang,Lu Wang,Qiuxia Li,Bo Wen,Duxin Sun,Shaomeng Wang

Journal of Medicinal Chemistryno. 7 (2024): 5275-5304

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Discovery of CBPD-409 As a Highly Potent, Selective, and Orally Efficacious CBP/p300 PROTAC Degrader for the Treatment of Advanced Prostate Cancer

Zhixiang Chen,Mi Wang,Dimin Wu,Lijie Zhao,Hoda Metwally,Wei Jiang,Yu Wang,Longchuan Bai,Donna Mceachern,Jie Luo,Meilin Wang,Qiuxia Li,Aleksas Matvekas,Bo Wen,Duxin Sun,Arul M. Chinnaiyan,Shaomeng Wang

Journal of Medicinal Chemistryno. 7 (2024): 5351-5372

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Discovery of AK-1690: A Potent and Highly Selective STAT6 PROTAC Degrader

Atsunori Kaneshige, Yiqing Yang,Longchuan Bai,Mi Wang,Renqi Xu,Leena Mallik,Krishnapriya Chinnaswamy,Hoda Metwally,Yu Wang,Donna McEachern,Jelena Tosovic,Chao-Yie Yang,Paul D. Kirchhoff,Jennifer L. Meagher,Jeanne A. Stuckey,Shaomeng Wang

JOURNAL OF MEDICINAL CHEMISTRY (2024)

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Orally Bioavailable PROTAC Based MDM2 Degrader

Angelo Aguilar,Jiuling Yang,Yangbing Li,Donna McEachern,Shaomeng Wang

Cancer Researchno. 6_Supplement (2024): 4515-4515

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Discovery of MD-265: A Potent MDM2 Degrader That Achieves Complete Tumor Regression and Improves Long-Term Survival of Mice with Leukemia

Angelo Aguilar,Jiuling Yang,Yangbing Li,Donna Mceachern,Liyue Huang, Stevenchoukry Razzouk,Shaomeng Wang

JOURNAL OF MEDICINAL CHEMISTRY（2024）

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Discovery of ERD-12310A As an Exceptionally Potent and Orally Efficacious PROTAC Degrader of Estrogen Receptor Α (Erα)

Rohan Kalyan Rej,Biao Hu, Zhixiang Chen,Ranjan Kumar Acharyya,Dimin Wu,Hoda Metwally,Donna Mceachern,Yu Wang,Wei Jiang,Longchuan Bai, Leticia S. Nishimura,Christina L. Gersch,Meilin Wang,Bo Wen,Duxin Sun,Kathryn Carlson,John A. Katzenellenbogen, Guozhang Xu,Weihong Zhang, Wenxue Wu, E. Scott Priestley,Zhihua Sui,James M. Rae,Shaomeng Wang

JOURNAL OF MEDICINAL CHEMISTRYno. 23 (2024): 20933-20965

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