Deborah Gill

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Bio

Deborah's research then began to focus on the potential of gene therapy for genetic diseases, developing a potential treatment for Cystic Fibrosis lung disease, and resulting in multiple clinical trials demonstrating proof of principle for CF gene therapy.

Research Interests

Papers共 280 篇Author StatisticsCo-AuthorSimilar Experts

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Pharmacological and Pre-Clinical Safety Profile of Rsiv.f/hn, a Hybrid Lentiviral Vector for Cystic Fibrosis Gene Therapy

Alena Moiseenko,Anthony Sinadinos,Ana Sergijenko,Kyriel Pineault,Aarash Saleh, Konradin Nekola, Nathalie Strang,Anastasia Eleftheraki,A. Christopher Boyd, Jane C. Davies,Deborah R. Gill,Stephen C. Hyde,Gerry Mclachlan,Tim Rath,Michael Rothe,Axel Schambach,Silke Hobbie,Michael Schuler,Udo Maier, Matthew J. Thomas,Detlev Mennerich,Manfred Schmidt,Uta Griesenbach,Eric W. F. W. Alton,Sebastian Kreuz

EUROPEAN RESPIRATORY JOURNALno. 1 (2025)

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Preclinical Optimisation of Lentiviral Delivery to Piglet Lungs for Gene Therapy of Surfactant Deficiencies

Craig McDougall, Cathy McLaughlin,Elisabeth Thornton,Christina Vrettou,Kamran Miah, Emily Castells,Rebecca Dean,Mariana A. Viegas,Stephen C. Hyde,Deborah R. Gill,Gerry McLachlan

MOLECULAR THERAPY（2024）

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P046 Lenticlair™-ON: an Extension Trial Examining Long-Term Safety and Efficacy Outcomes Associated with an Inhaled F/HN-pseudotyped Lentiviral Vector for CF Gene Therapy in People with Cystic Fibrosis

J.C. Davies,M.A. Mall,D. Polineni,S.H. Donaldson,I. Fajac,R. Jain, B.K. Rubin,A.C. Boyd,D.R. Gill,U. Griesenbach,S.C. Hyde,G. McLachlan,V. Kohlbrenner,R. Sigmund, A. Engel, A. Gupta,E. Alton

Journal of Cystic Fibrosis (2024): S80-S80

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P045 Lenticlair™ 1: A Phase 1/2 Trial Evaluating the Safety, Tolerability and Efficacy of an Inhaled F/HN-pseudotyped Lentiviral Vector for CF Gene Therapy in People with CF Ineligible for CFTR Modulators

J.C. Davies,M.A. Mall,D. Polineni,S.H. Donaldson,I. Fajac, R. Jain, B.K. Rubin,A.C. Boyd,D.R. Gill,U. Griesenbach,S.C. Hyde,G. McLachlan,M. Avis,C. Diefenbach,R. Sigmund,W. Seibold, A. Gupta,E. Alton

Journal of Cystic Fibrosis (2024): S80-S80

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WS10.01 Administration of Lentiviral Vector Doses Achieving High Transduction Efficiency is Well Tolerated in Mice

U. Griesenbach,G. McLachlan,A. Sinadinos, C. Cheminay,J. Ashour,C. Meng, E. Castells, R. Dean, M.A. Viegas,A.C. Boyd,J.C. Davies,D.R. Gill,S.C. Hyde,N. Strelkowa,E.W. Alton

Journal of Cystic Fibrosis (2024): S18-S18

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A Roadmap to Precision Treatments for Familial Pulmonary Fibrosis

Killian Hurley,Mari Ozaki,Quentin Philippot,Liam Galvin, David Crosby,Mary Kirwan,Deborah R. Gill,Konstantinos-Dionysios Alysandratos,Gisli Jenkins,Matthias Griese,Nadia Nathan,Raphael Borie

EBioMedicine (2024): 105135-105135

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Traceless Delivery of Genome Editors

Jakob Hansen Haldrup,Deborah R. Gill,Stephen Hyde

MOLECULAR THERAPYno. 4 (2024): 210-211

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Lentiviral Gene Therapy for Cystic Fibrosis: A Promising Approach and First-In-Human Trial

Jane C Davies,Deepika Polineni,A Christopher Boyd,Scott Donaldson,Deborah R Gill,Uta Griesenbach,Stephen C Hyde,Raksha Jain,Gerry McLachlan,Marcus A Mall,Eric W F W Alton

American Journal of Respiratory and Critical Care Medicine（2024）

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Rescue of Lethal SP-B Deficiency in a Murine Model Using Lentiviral Vector-Mediated Gene Therapy

Kamran M. Miah, Aimee Ruffle,Mariana A. Viegas, Emily Castells,Hamid Dolatshad,Stephanie G. Sumner-Jones,Rebecca Dean,Yue Du, Alexandra McStea,Rosie J. Munday,Altar M. Munis,Stephen C. Hyde,Deborah R. Gill

MOLECULAR THERAPYno. 4 (2024): 40-40

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WS17.06 F/HN Pseudotyped Lentiviral Vector-Mediated Transduction of Non-Human Primates

U. Griesenbach,G. McLachlan,A. Sinadinos, C. Cheminay,J. Ashour,C. Meng, E. Castells, R. Dean,M.A. Viegas,A.C. Boyd,J.C. Davies,D.R. Gill,S.C. Hyde,D. Blanset,E.W. Alton

Journal of Cystic Fibrosis (2023): S33-S33

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Papers共 280 篇Author StatisticsCo-AuthorSimilar Experts