The general subject areas of research expertise of this laboratory are platelet biology, complement biochemistry and blood coagulation. Our particular experimental focus in transfusion medicine is in the area of blood product processing and storage. Ongoing research projects include studies of the storage lesion of platelet concentrates and methods to improve the quality of stored platelet concentrates. Most recently, we have sought to apply leading edge technology to these research questions, in particular through the application of proteomics technology to investigations of blood products.
The research in the laboratory also includes a significant component of applied development work with projects related to practical solutions to issues arising in the manufacture of blood products including process control and quality enhancement through modification of production processes or through understanding more about the significance of the variability of donor characteristics. We have ongoing collaborations with other scientists in all of these areas as well as collaborations with companies working in the blood transfusion business.