David Lye - National Centre for Infectious Diseases

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Professor Lye has held more than SGD$13million in research grant as principal investigator to date. His research interests are in COVID-19, dengue and antimicrobial resistance. He has published more than 350 peer-reviewed manuscripts in journals such as NEJM, Lancet, JAMA, JAMA Oncology, Lancet Respiratory Medicine, Lancet Infectious Diseases, Lancet Microbe, Lancet Global Health, Annals Internal Medicine as well as Science, Nature Biotechnology, Nature Reviews Immunology, Nature Microbiology, Nature Communications, Science Translational Medicine, Journal Clinical Investigation and Journal Experimental Medicine.

Research Interests

Papers共 478 篇Author StatisticsCo-AuthorSimilar Experts

By YearBy Citation主题筛选期刊级别筛选合作者筛选合作机构筛选

Evaluating the Effectiveness of International Travel Controls to Identify Monkeypox Virus Infected Travelers

Keisuke Ejima, Yuqian Wang,Akira Endo,Hiroaki Murayama,Yun Shan Goh,Alex R. Cook,Yong Dam Jeong,Shingo Iwami,Hyeongki Park,Borame Dickens,Shihui Jin,Jue Tao Lim, Conrad Chan,Po Ying Chia,Barnaby Young, Yang, Martin Chio,David Lye,Marco Ajelli

crossref（2025）

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Elevated Plasma Angiopoietin-like 4 Protein Levels in Adult Patients with Dengue

Win Khaing,Suk Hiang Lau,Tun-Linn Thein,Nguan Soon Tan,Sylvie Alonso,Shawn Vasoo,Po Ying Chia,David Chien Boon Lye,Yee Sin Leo,Vincent T K Chow

Virusesno. 2 (2025)

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Bivalent Boosters and Risk of Postacute Sequelae Following Vaccine-Breakthrough SARS-CoV-2 Omicron Infection: A Cohort Study

Liang En Wee,Jue Tao Lim, Mayank Goel, Muhammad Ismail Abdul Malek,Calvin J Chiew,Benjamin Ong,David Chien Boon Lye,Kelvin Bryan Tan

Clinical infectious diseases an official publication of the Infectious Diseases Society of Americano. 3 (2025): 520-528

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Convalescent Plasma for the Treatment of Patients with COVID-19: the Singapore Experience and Lessons Learnt

Jun Yang Tay, Sharavan Sadasiv Mucheli,Bingwen Eugene Fan, Sing-Zern Fong, Chek Kia Boo,Ying Ding, Wanni Chia,Chee Wah Tan, Barnaby Young,Poh Lian Lim,Yee Sin Leo, Suma Rao, Ai Leen Ang, Allison Tso, Venkata Sreekanth Sampath, Stephrene Seok Wei Chan,Ponnudurai Kuperan, Christopher Dheepa, Wah, Ah Eng Ang, Connie Siew Ping Chen, Laurence Sandig,David Lye,Lin-Fa Wang,Kiat Hoe Ong,Shawn Vasoo

Singapore medical journal (2025)

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Nirmatrelvir/ritonavir Treatment and Risk for Post-Acute Sequelae of COVID-19 in Older Singaporeans

Liang En Wee,Jue Tao Lim,An Ting Tay,Calvin J. Chiew,Barnaby Edward Young,Betty Wong,Ruth Lim,Ching Li Lee,Joyce Tan,Shawn Vasoo,David Chien Lye,Kelvin Bryan Tan

CLINICAL MICROBIOLOGY AND INFECTION（2025）

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SARS-CoV-2 Mrna Vaccines Induce Cross-Reactive Antibodies to NL63 Coronavirus but Do Not Boost Pre-Existing Immunity Anti-NL63 Antibody Responses

Weiyi Tang,Zi Wei Chang,Yun Shan Goh, Yong Jie Tan,Pei Xiang Hor,Chiew Yee Loh,David C Lye, Barnaby E Young,Lisa F P Ng,Matthew Zirui Tay,Laurent Rénia, On Behalf Of The Covid-Cohort Study Group, Ncid Study Group, Covid Clinicians' Group

Vaccinesno. 3 (2025)

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Defining the Critical Requisites for Accurate Simulation of SARS-CoV-2 Viral Dynamics: Patient Characteristics and Data Collection Protocol

Hoong Kai Chua, Ananya Singh, Yuqian Wang,Yun Shan Goh, Conrad En Zuo Chan,Jean-Marc Chavatte,Raymond Valentine Tzer Pin Lin,Yvonne C. F. Su,Marco Ajelli,Po Ying Chia,Sean W. X. Ong,David Chien Lye,Barnaby E. Young,Keisuke Ejima

JOURNAL OF MEDICAL VIROLOGYno. 1 (2025)

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Severity of Respiratory Syncytial Virus Versus SARS-CoV-2 Omicron and Influenza Infection Amongst Hospitalized Singaporean Adults: a National Cohort Study

Liang En Wee,Jue Tao Lim, Reen Wan Li Ho,Calvin J Chiew,Barnaby Young,Indumathi Venkatachalam,Jean Xiang Ying Sim, Hau Yiang Cheong,Tong Yong Ng,Chee-Fu Yung,David Chien Boon Lye,Kelvin Bryan Tan

The Lancet regional health Western Pacific (2025): 101494-101494

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Bivalent Boosters and Risk of Postacute Sequelae Following Vaccine-Breakthrough Severe Acute Respiratory Syndrome Coronavirus 2 Omicron Infection: A Cohort Study

Liang En Wee,Jue Tao Lim, Mayank Goel, Muhammad Ismail Abdul Malek,Calvin J. Chiew,Benjamin Ong,David Chien Boon Lye,Kelvin Bryan Tan

CLINICAL INFECTIOUS DISEASES (2025)

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COVID-19 Vaccination Before or During Pregnancy Results in High, Sustained Maternal Neutralizing Activity to SARS-CoV2 Wild-Type and Delta/Omicron Variants of Concern, Particularly Following a Booster Dose or Infection

Aniza P. Mahyuddin,Hannah L. F. Swa,Ruifen Weng, Jingxian Zhang, Janice P. Dhanaraj, Binny P. Sesurajan,Mary Rauff,Pradip Dashraath,Abhiram Kanneganti, Rachel Lee,Lin-Fa Wang,Barnaby E. Young,Paul A. Tambyah,David C. Lye,Louis Y. A. Chai,Sidney Yee,Mahesh Choolani,Citra N. Z. Mattar

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES（2024）

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