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Bio
I am a Clinical Pharmacologist funded by an MRC Clinician Scientist Fellowship.
My fellowship is investigating the role of microglia in brain disease. Microglia are referred to as the “policemen of the brain” because they activate in response to almost any brain injury, including degenerative disease like Alzheimer’s and Parkinson’s. The way in which microglia respond to these diseases is very important, because this response partly determines how fast the disease progresses. My focus is on identifying drugs to modulate their responses and therefore slow the progression of these diseases.
In addition, I am Head of Clinical Studies at the NIHR Imperial Clinical Research Facility, a unit which helps Imperial College researchers turn their laboratory discoveries into medicines of the future. At the moment, we are focussed almost exclusively on COVID-19, examining both vaccines and potential treatments.
I spend the remaining ~20% of my time in clinical medicine seeing patients on the acute medical take, leading Pharmacology teaching (with Chris John) at Imperial Medical School, and contributing to committees on the use of medicines. This includes chairing the North West London Integrated Formulary Committee which covers GP practices responsible for approximately 2.6 million people, and chairing the Subregional IVIG committee covering the stewardship of this life saving but scarce resource across 6 NHS Trusts.
If you are interested in working on any of these projects, or wanting to start a new one in this field, please do get in touch.
My fellowship is investigating the role of microglia in brain disease. Microglia are referred to as the “policemen of the brain” because they activate in response to almost any brain injury, including degenerative disease like Alzheimer’s and Parkinson’s. The way in which microglia respond to these diseases is very important, because this response partly determines how fast the disease progresses. My focus is on identifying drugs to modulate their responses and therefore slow the progression of these diseases.
In addition, I am Head of Clinical Studies at the NIHR Imperial Clinical Research Facility, a unit which helps Imperial College researchers turn their laboratory discoveries into medicines of the future. At the moment, we are focussed almost exclusively on COVID-19, examining both vaccines and potential treatments.
I spend the remaining ~20% of my time in clinical medicine seeing patients on the acute medical take, leading Pharmacology teaching (with Chris John) at Imperial Medical School, and contributing to committees on the use of medicines. This includes chairing the North West London Integrated Formulary Committee which covers GP practices responsible for approximately 2.6 million people, and chairing the Subregional IVIG committee covering the stewardship of this life saving but scarce resource across 6 NHS Trusts.
If you are interested in working on any of these projects, or wanting to start a new one in this field, please do get in touch.
Research Interests
Papers共 241 篇Author StatisticsCo-AuthorSimilar Experts
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Gianmarco Abbadessa, Ai Nagano,Simon Hametner,Owain Howell,David Owen, Artemis Papadaki,Prashant Srivastava, Simona Bonavita,Roberta Magliozzi,Richard Reynolds,Mie Rizig,Richard Nicholas
Annals of neurology (2025)
Journal of Neuroinflammationno. 1 (2025): 1-16
Owain Howell, B. J. Cooze, I. Farkas, J. Oliveira, Y. Y. Leung,G. Abbadessa, G. Santiago,Djordje Gveric, P. Srivastava,J. W. Neal,Richard Nicholas,David Owen,Richard Reynolds
MULTIPLE SCLEROSIS JOURNALno. 3 (2024): 98-99
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CLINICAL PHARMACOLOGY & THERAPEUTICS (2024): S63-S63
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JOURNAL OF NEUROVIROLOGYno. 2 (2024): 165-175
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICSno. 2 (2024): S143-S143
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICSno. 2 (2024): E237-E238
CLINICAL PHARMACOLOGY & THERAPEUTICS (2024): S43-S44
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B. To, S. Farid,S. Zhao, M. Li, N. Amirmokhtari,L. Wei,R. Memmott,A. Alahmadi,K. He,J. Kaufman, L. Roof,P. Shields,D. Carbone,G. Otterson,C. Presley,D. Owen
Journal of Thoracic Oncologyno. 10 (2024): S644-S645
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Author Statistics
#Papers: 241
#Citation: 6389
H-Index: 44
G-Index: 78
Sociability: 7
Diversity: 3
Activity: 31
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