He has clinical interests in the areas of surgery for benign and malignant oesophageal disease, upper gastrointestinal surgery, advanced laparoscopic surgery and interventional endoscopy. He has been active in the development of laparoscopic and endoscopic surgery in Australia, pioneering the development and evaluation of laparoscopic surgery for gastro-oesophageal reflux, oesophageal motility disorders, and oesophageal cancer. He has linked this activity to the evaluation and refinement of techniques within prospective randomised clinical trials. He has authored more than 450 refereed research papers and book chapters. Since 1997 he has also received 19 major research grants from NHMRC, MRFF and NIH, as well as major grant support from other funding bodies. In 2015 he was elected as a Fellow of the Australian Academy of Health and Medical Sciences (FAHMS), and appointed a Matthew Flinders Distinguished Professor at Flinders University