Dongmei Zhao - Key Laboratory of Structure‐Based Drug Design and Discovery of the Ministry of Education, Shenyang Pharmaceutical University

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Discovery of Highly Selective CYP1B1 Inhibitors

Ting Wang, Haoyu Zhang, Dihan Tan, Ningyi Qin, Bohou Song, Pengfei Song,Yang Liu,Dongmei Zhao,Gang Xing,Maosheng Cheng

Journal of medicinal chemistry (2025)

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Discovery of a Potent, Broad-Spectrum and in Vivo Effective Deuterated Tetrazole CYP51 Inhibitor

Zirui Luo, Rongrong Liu, Yixiang Sun, Leimeng Zhao, Jiachen Zhang, Kejian Li, Zixuan Gao, Nian Liu, Haoyu Zhang, Xudong Wu, Jingming Liu, Wenzhan Hao, Xin Su,Dongmei Zhao,Maosheng Cheng

European journal of medicinal chemistry (2025): 117817-117817

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Rational Design of CZL-S092: A Novel Indazole-Based PLK4 Inhibitor Targeting Neuroblastoma Through Virtual Screening and Fragment-Based Drug Design Strategies

Nian Liu, Ningyuan Hu, Cunzheng Fan, Minghui Tong, Xuan Shi, Han Wang, Pengkun Sun, Shuyi Mu, Zehui Qi, Wenqiang Sun, Haoyu Zhang, Yixiang Sun, Zixuan Gao,Dongmei Zhao,Maosheng Cheng

European journal of medicinal chemistry (2025): 117867-117867

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Design, Synthesis, and Biological Evaluation of Selective PAK4 Degrader for the Treatment of Lung Tumor Metastasis

Hanxun Wang, Peilu Song, Yujie Wang,Hanqing Xu, Lanlan Shen, Zhuo Qi, Lu Chen, Lanyan Ma, Zhijian Wang, Xingqi Hu, Wanqing Wang, Na Li, Yage Yu, Yinli Gao, Mingyu Xia,Dongmei Zhao,Jian Wang,Maosheng Cheng

Journal of medicinal chemistryno. 11 (2025): 11231-11269

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Design, Synthesis, and Biological Activity Evaluation of Deuterated Diphenyl Azole Alcohol-Based CYP51 Inhibitors

Yixiang Sun, Zirui Luo, Kejian Li, Hongjian Wang, Zixuan Gao, Jiachen Zhang, Rongrong Liu, Rui Liu, Xudong Wu, Nian Liu, Haoyu Zhang, Xin Su, Wenbo Yin,Dongmei Zhao,Maosheng Cheng

Journal of medicinal chemistryno. 11 (2025): 12229-12257

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Design, Synthesis, and Biological Evaluation of Novel N-(1H-indazol-6-yl)benzenesulfonamide Derivatives As Potent PLK4 Inhibitors

Pengkun Sun, Cunzheng Fan, Nian Liu, Minghui Tong, Xuan Shi, Han Wang, Shuyi Mu, Ningyuan Hu, Yixiang Sun, Haoyu Zhang, Zixuan Gao,Dongmei Zhao,Maosheng Cheng

RSC medicinal chemistry (2025)

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[Retracted] (‑)‑β‑hydrastine Suppresses the Proliferation and Invasion of Human Lung Adenocarcinoma Cells by Inhibiting PAK4 Kinase Activity