Eric A. Sigel - X Chem Pharmaceut | 人才画像

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论文共 16 篇作者统计合作学者相似作者

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A Resource to Enable Chemical Biology and Drug Discovery of WDR Proteins

Suzanne Ackloo,Fengling Li,Magda Szewczyk,Almagul Seitova,Peter Loppnau,Hong Zeng,Jin Xu,Shabbir Ahmad, Yelena A Arnautova, AJ Baghaie,Serap Beldar,Albina Bolotokova,Paolo A Centrella,Irene Chau,Matthew A Clark,John W Cuozzo, Saba Dehghani-Tafti,Jeremy S Disch,Aiping Dong, Antoine Dumas,Jianwen A. Feng,Pegah Ghiabi,Elisa Gibson,Justin Gilmer,Brian Goldman,Stuart R Green,Marie-Aude Guié,John P Guilinger,Nathan Harms, Oleksandra Herasymenko,Scott Houliston,Ashley Hutchinson,Steven Kearnes,Anthony D Keefe,Serah W Kimani,Trevor Kramer, Maria Kutera, Haejin A Kwak,Cristina Lento,Yanjun Li, Jenny Liu,Joachim Loup,Raquel AC Machado,Christopher J Mulhern,Sumera Perveen, Germanna L Righetto,Patrick Riley, Suman Shrestha,Eric A Sigel, Madhushika Silva, Michael D. Sintchak,Belinda L Slakman, Rhys D Taylor, James Thompson,Wen Torng, Carl Underkoffler,Moritz von Rechenberg,Ian Watson,Derek J Wilson,Esther Wolf, Manisha Yadav, Aliakbar K Yazdi,Junyi Zhang,Ying Zhang,Vijayaratnam Santhakumar,Aled M Edwards,Dalia Barsyte-Lovejoy,Matthieu Schapira,Peter J Brown,Levon Halabelian,Cheryl H Arrowsmith

biorxiv（2024）

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A Target Class Ligandability Evaluation of WD40 Repeat-Containing Proteins

Suzanne Ackloo,Fengling Li,Magda Szewczyk,Almagul Seitova,Peter Loppnau,Hong Zeng,Jin Xu,Shabbir Ahmad, Yelena A. Arnautova, A. J. Baghaie,Serap Beldar,Albina Bolotokova,Paolo A. Centrella,Irene Chau,Matthew A. Clark,John W. Cuozzo, Saba Dehghani-Tafti,Jeremy S. Disch,Aiping Dong, Antoine Dumas,Jianwen A. Feng,Pegah Ghiabi,Elisa Gibson,Justin Gilmer,Brian Goldman,Stuart R. Green,Marie-Aude Guie,John P. Guilinger,Nathan Harms, Oleksandra Herasymenko,Scott Houliston,Ashley Hutchinson,Steven Kearnes,Anthony D. Keefe,Serah W. Kimani,Trevor Kramer, Maria Kutera, Haejin A. Kwak,Cristina Lento,Yanjun Li, Jenny Liu,Joachim Loup,Raquel A. C. Machado,Christopher J. Mulhern,Sumera Perveen, Germanna L. Righetto,Patrick Riley, Suman Shrestha,Eric A. Sigel, Madhushika Silva, Michael D. Sintchak,Belinda L. Slakman, Rhys D. Taylor, James Thompson,Wen Torng, Carl Underkoffler,Moritz von Rechenberg,Ryan T. Walsh,Ian Watson,Derek J. Wilson,Esther Wolf, Manisha Yadav, Aliakbar K. Yazdi, Junyi Zhang,Ying Zhang,Vijayaratnam Santhakumar,Aled M. Edwards,Dalia Barsyte-Lovejoy,Matthieu Schapira,Peter J. Brown,Levon Halabelian,Cheryl H. Arrowsmith

Journal of medicinal chemistryno. 2 (2024): 1092-1112

引用0浏览0WOS引用

Development of Potent Mcl-1 Inhibitors: Structural Investigations on Macrocycles Originating from a DNA-Encoded Chemical Library Screen

Koen F. W. Hekking,Sergio Maroto, Kees van Kekem, Frank S. Haasjes,Jack C. Slootweg, Patrick G. B. Oude Alink, Ron Dirks,Malvika Sardana, Marjon G. Bolster, Brian Kuijpers, Dennis Smith, Robin Doodeman,Marcel Scheepstra,Birgit Zech,Mark Mulvihill,Louis M. Renzetti,Lee Babiss,Paolo A. Centrella,Matthew A. Clark,John W. Cuozzo,Marie-Aude Guie,Eric Sigel,Sevan Habeshian,Christopher D. Hupp,Julie Liu,Heather A. Thomson,Ying Zhang,Anthony D. Keefe, Gerhard Muller, Stijn Gremmen

Journal of Medicinal Chemistryno. 4 (2024): 3039-3065

引用3浏览0WOS引用

Discovery of Novel UDP-N-Acetylglucosamine Acyltransferase (LpxA) Inhibitors with Activity against Pseudomonas aeruginosa

M. Dominic Ryan,Alastair L. Parkes,David Corbett,Anthony P. Dickie,Michelle Southey,Ole A. Andersen,Daniel B. Stein,Olivier R. Barbeau, Angelo Sanzone,Pia Thommes,John Barker,Ricky Cain,Christel Compper, Magali Dejob,Alain Dorali, Donnya Etheridge, Sian Evans,Adele Faulkner,Elise Gadouleau,Timothy Gorman, Denes Haase,Maisie Holbrow-Wilshaw,Thomas Krulle, Xianfu Li,Christopher Lumley, Barbara Mertins,Spencer Napier,Rajesh Odedra,Kostas Papadopoulos, Vasileios Roumpelakis, Kate Spear,Emily Trimby,Jennifer Williams,Michael Zahn,Anthony D. Keefe,Ying Zhang,Holly T. Soutter,Paolo A. Centrella,Matthew A. Clark,John W. Cuozzo,Christoph E. Dumelin, Boer Deng,Avery Hunt,Eric A. Sigel,Dawn M. Troast,Boudewijn L. M. DeJonge

JOURNAL OF MEDICINAL CHEMISTRY（2021）

引用16浏览0WOS引用

Machine Learning on DNA-encoded Libraries: A New Paradigm for Hit-Finding

Kevin McCloskey,Eric A. Sigel,Steven Kearnes,Ling Xue,Xia Tian, Dennis Moccia,Diana Gikunju,Sana Bazzaz,Betty Chan,Matthew A. Clark,John W. Cuozzo,Marie-Aude Guie,John P. Guilinger,Christelle Huguet,Christopher D. Hupp,Anthony D. Keefe,Christopher J. Mulhern,Ying Zhang,Patrick Riley

Journal of Medicinal Chemistryno. 16 (2020): 8857-8866

引用97浏览0EIWOS引用

Novel Autotaxin Inhibitor for the Treatment of Idiopathic Pulmonary Fibrosis: A Clinical Candidate Discovered Using DNA-Encoded Chemistry

John W. Cuozzo,Matthew A. Clark,Anthony D. Keefe,Anna Kohlmann,Mark Mulvihill,Haihong Ni,Louis M. Renzetti,Daniel Resnicow,Frank Ruebsam,Eric A. Sigel,Heather A. Thomson, Ce Wang,Zhifeng Xie,Ying Zhang

Journal of Medicinal Chemistry（2020）

引用80浏览0WOS引用

Discovery Of Pan-Active And Isoform Selective Inhibitors Of Class I Phosphoinositide-3-Kinases (Pi3ks) Utilizing A Dna-Encoded Discovery Platform

Christopher Hupp,Daniel Resnicow,Diana Gikunju,Matthew Clark,Ying Zhang,Anthony Keefe,John Cuozzo,Eric Sigel,Paolo Centrella,Marie-Aude Guie,Sevan Habeshian,Kaitlyn Kennedy

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY (2017)

引用0浏览0引用

Corrigendum: Discovery of a Potent BTK Inhibitor with a Novel Binding Mode by Using Parallel Selections with a DNAEncoded Chemical Library

J. W. Cuozzo,P. A. Centrella,D. Gikunju,S. Habeshian,C. D. Hupp, A. D. Keefe,E. A. Sigel,H. H. Soutter,H. A. Thomson,Y. Zhang, M. A. Clark

ChemBioChem（2017）

引用64浏览0WOS引用

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