Dr. Zhang is a molecular biologist focused on improving human health. He played an integral role in the development of two revolutionary technologies, optogenetics and CRISPR-Cas systems, including pioneering the use of Cas9 for genome editing and discovering CRISPR-Cas12 and Cas13 systems and developing them for therapeutic and diagnostic applications. Current research in the Zhang laboratory is centered on the discovery of novel biological systems and processes, uncovering their mechanisms, and developing them into molecular tools and therapies to study and treat human disease. Zhang is a core member of the Broad Institute, an Investigator at the McGovern Institute for Brain Research, the James and Patricia Poitras Professor of Neuroscience at MIT, and a Howard Hughes Medical Investigator. He is also a member of the National Academy of Sciences, the National Academy of Medicine, and the American Academy of Arts and Sciences as well as a fellow in the National Academy of Inventors.