基本信息
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个人简介
I am an Associate Professor and the Graduate Program Director in the Department of Pharmacology & Toxicology. Throughout my career I have gained significant expertise in the field of molecular and cellular neuroscience and pharmacology which built on a background in the medical field in neurology and psychiatry. My overall research goal is to advance the understanding and therapies of disorders associated with nerve function by identifying key molecular determinants of intrinsic neuronal properties and synaptic integration that might be mechanistically linked to the biological cause of the disease. Currently, our approach spans from in vitro to animal-based assays including electrophysiology, high-resolution imaging, biochemistry, biophysics, molecular biology and bioluminescence-based technology for drug discovery targeting ion channels involved in nerve function. Over the course of the past years we targeted the protein:protein interactions (PPI) at the level of voltage-gated Na+ channels and discovered mechanisms of regulation of neuronal excitability on the basis of intracellular FGFs. This research has opened new horizons in neuropharmacology revealing potential druggable sites suitable for the development of novel allosteric modulators of Nav channels. Since at UTMB I have secured three funded R01 grants as PI or MPI and a number of private foundations or internal grants. I have been actively training PhD, undergraduate and high school students in my laboratory. Since 2017 I have also taken over the Graduate Program of Pharmacology & Toxicology as Director.
研究兴趣
论文共 119 篇作者统计合作学者相似作者
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Francesca Montarolo, Anita Maria Rominto, Luna Berrino, Antonio Bertolotto,Fernanda Laezza, Filippo Tempia,Eriola Hoxha
Translational psychiatryno. 1 (2025): 136-136
T.J. Baumgartner, N.M. Dvorak, N.A. Goode, Z. Haghighijoo, M. Marosi, J. Singh, A.K. Singh,F. Laezza
Nolan M. Dvorak,Paul A. Wadsworth,Guillermo Aquino-Miranda,Pingyuan Wang,Douglas S. Engelke,Jingheng Zhou,Nghi Nguyen,Aditya K. Singh,Giuseppe Aceto,Zahra Haghighijoo, Isabella I. Smith, Nana Goode,Mingxiang Zhou, Yosef Avchalumov,Evan P. Troendle,Cynthia M. Tapia,Haiying Chen,Reid T. Powell,Timothy J. Baumgartner, Jully Singh, Leandra Koff,Jessica Di Re, Ann E. Wadsworth,Mate Marosi,Marc R. Azar, Kristina Elias, Paul Lehmann,Yorkiris M. Marmol Contreras,Poonam Shah, Hector Gutierrez,Thomas A. Green,Martin B. Ulmschneider,Marcello D'Ascenzo,Clifford Stephan,Guohong Cui,Fabricio H. Do Monte,Jia Zhou,Fernanda Laezza
NATURE COMMUNICATIONSno. 1 (2025)
Jessica Di Re,Michela Marini, Syed Ibrar Hussain,Aditya K. Singh, Akshaya Venkatesh,Musaad A. Alshammari,Tahani K. Alshammari,Abdul-Rizaq Ali Hamoud,Ali Sajid Imami,Zahra Haghighijoo, Nickolas Fularcyzk,Laura Stertz, Derek Hawes,Angela Mosebarger, Jordan Jernigan, Claire Chaljub,Ralda Nehme,Consuelo Walss-Bass,Anton Schulmann,Marquis P. Vawter,Robert Mccullumsmith,Robert D. Damoiseaux,Agenor Limon,Demetrio Labate,Michael F. Wells,Fernanda Laezza
MOLECULAR PSYCHIATRY (2025)
Jessica Di Re, Leandra Koff, Yosef Avchalumov,Aditya K. Singh,Timothy J. Baumgartner,Mate Marosi,Lisa M. Matz,Lance M. Hallberg,Bill T. Ameredes, Erin H. Seeley,Shelly A. Buffington,Thomas A. Green,Fernanda Laezza
JOURNAL OF HAZARDOUS MATERIALS (2025)
Jessica Di Re, Leandra Koff, Yosef Avchalumov,Aditya K. Singh, Timothy B. Baumgartner,Mate Marosi,Lisa M. Matz,Lance M. Hallberg, Ameredes, Erin H. Seeley,Shelly A. Buffington,Thomas A. Green,Fernanda Laezza
NEUROPSYCHOPHARMACOLOGY (2024): 357-358
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INTERNATIONAL JOURNAL OF MOLECULAR SCIENCESno. 15 (2024)
L. Koff, J. Di Re, S. Chand, Y. Avchalumov, N.M. Nguyen, T.J. Baumgartner, A.K. Singh, N.A. Goode, M. Marosi,L.M. Hallberg,B.T. Ameredes, T.A. Green,S.V. Yelamanchili,G. Pendyala,F. Laezza
Molecular & Cellular Proteomicspp.100902, (2024)
Nolan M. Dvorak,Nadia D. Domingo,Cynthia M. Tapia,Paul A. Wadsworth,Mate Marosi, Yosef Avchalumov,Chanida Fongsaran, Leandra Koff,Jessica Di Re,Catherine M. Sampson,Timothy J. Baumgartner,Pingyuan Wang,Paula P. Villarreal,Olivia D. Solomon,Sonja J. Stutz, Aditi, Jacob Porter,Komi Gbedande,Brendan Prideaux,Thomas A. Green, Erin H. Seeley,Parimal Samir, Kelley T. Dineley,Gracie Vargas,Jia Zhou,Irma Cisneros,Robin Stephens,Fernanda Laezza
JOURNAL OF NEUROINFLAMMATIONno. 1 (2023)
NEUROPSYCHOPHARMACOLOGY (2023): 390-391
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作者统计
#Papers: 119
#Citation: 2855
H-Index: 29
G-Index: 51
Sociability: 6
Diversity: 3
Activity: 14
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