Giovanna Scapin

基本信息

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职业迁徙

个人简介

Scapin, an accomplished crystallographer, worked at Merck for 23 years in the field of protein structures and structure-guided drug discovery.

研究兴趣

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Structure Guided Discovery of Novel Pan Metallo-β-Lactamase Inhibitors with Improved Gram-Negative Bacterial Cell Penetration

JOURNAL OF MEDICINAL CHEMISTRY（2024）

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Quantitation and Characterization of Serotype 6A Activation for Pneumococcal Conjugate Vaccine by Cryo-Em and SEC Methods

Mingxiang Lin,James Z. Deng,Giovanna Scapin, Yue Yuan,Yacob Gomez-Llorente,Weidong Tong,Richard Porambo, Jongrock Kong, Nori Ikemoto,Catherine Lancaster,Jason Kaelber,Michael Winters,Ping Zhuang

Vaccineno. 25 (2024): 126067-126067

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Structural Biology in Drug Discovery Through the (orange) Years

Giovanna Scapin

ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES（2024）

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Mechanistic Insights into a Heterobifunctional Degrader-Induced PTPN2/N1 Complex

Qi Hao, Manoj K. Rathinaswamy,Kelly L. Klinge,Matthew Bratkowski,Amirhossein Mafi,Christina K. Baumgartner,Keith M. Hamel, Gesine K. Veits,Rinku Jain,Claudio Catalano,Mark Fitzgerald, Alexander W. Hird,Eunice Park, Harit U. Vora,James A. Henderson,Kenton Longenecker,Charles W. Hutchins,Wei Qiu,Giovanna Scapin,Qi Sun,Vincent S. Stoll,Chaohong Sun, Ping Li,Dan Eaton,David Stokoe,Stewart L. Fisher,Christopher G. Nasveschuk,Marcia Paddock,Michael E. Kort

COMMUNICATIONS CHEMISTRYno. 1 (2024)

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High-Resolution Cryo-Electron Microscopy Structure Determination of Haemophilus Influenzae Tellurite-Resistance Protein A Via 200 Kv Transmission Electron Microscopy

Nhi L. Tran, Skerdi Senko, Kyle W. Lucier, Ashlyn C. Farwell, Sabrina M. Silva, Phat V. Dip,Nicole Poweleit,Giovanna Scapin,Claudio Catalano

International Journal of Molecular Sciences（2024）

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The CryoEM Structure of Human Serum Albumin in Complex with Ligands

Claudio Catalano, Kyle W. Lucier, Dennis To, Skerdi Senko, Nhi L. Tran, Ashlyn C. Farwell, Sabrina M. Silva,Phat Dip,Nicole Poweleit,Giovanna Scapin

Journal of Structural Biologyno. 3 (2024): 108105-108105

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Cerastecin Inhibition of the Lipooligosaccharide Transporter MsbA to Combat Acinetobacter Baumannii: from Screening Impurity to in Vivo Efficacy

JOURNAL OF MEDICINAL CHEMISTRYno. 17 (2024): 15620-15675

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Discovery of Sulfone Containing Metallo-Β-lactamase Inhibitors with Reduced Bacterial Cell Efflux and Histamine Release Issues

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2024)

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Traditional Educational Methods to Create the Future Generation of Crystallographers: the International School of Crystallography (Iscoc)

A. Guerri,P. Spadon,G. Scapin

Acta Crystallographica Section A Foundations and Advancesno. a2 (2023)

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论文共 160 篇作者统计合作学者相似作者