RESEARCH INTERESTS:
1. Epidemiology of viral hepatitis:
Conducting longitudinal studies to delineate the incidence and determinants (including viral, host, and environmental factors) of milestone transitions and disease progression in the natural history of chronic hepatitis B and C.
Recently, the focus has been on employing full-length deep sequencing of the hepatitis B virus to comprehend the distribution of quasispecies and variants in chronic hepatitis B patients. Investigations are underway to understand how these viral quasispecies interact with human genetic and immune factors, influencing the progression of the disease.

2. Development of risk prediction scores: Deriving and validating risk prediction tools which integrate multiple clinical parameters to predict the progression and adverse sequelae of chronic hepatitis B and C.

3. Health outcomes and high-risk groups for people with fatty liver and metabolic disorders

4. Biomarkers for early cancer detection: Exploring multi-omics pre-diagnostic biosignatures with potential for predicting major cancers.