His main research interests are clinical trials and translational research in gastrointestinal cancers and lymphoma. He is the chief or principal investigator of multiple phase I, II and III clinical trials evaluating novel treatment strategies and agents in various cancer signalling pathways.

He serves or has served on American Society of Clinical Oncology (ASCO) Scientific Program Committee, ASCO Education Committee, European Society of Medical Oncology (ESMO) Congress Steering Committee, ESMO Asia Scientific Programme and Steering Committee, ESMO Educational Committee and UK National Cancer Research Institute (NCRI) Colorectal Cancer and Pancreatic Cancer Clinical Study Groups, He will be track leaders for Gastrointestinal (non-colorectal) Cancer for ASCO Annual Meeting Education Committee and ESMO Scientific Committee as well as Scientific Chairman for ESMO Asia Congress in 2019.