Ian Watson

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Bio

Our work has identified a number of novel significantly mutated genes in melanomas, which possess hotspot mutations in coding and non-coding regions. Based on the frequency and correlation of the most frequently significantly mutated genes, we established a framework for genomic classification into one of four subtypes: mutant BRAF, RAS, NF1, and Triple-WT (wild-type) melanomas.

Research Interests

Papers共 87 篇Author StatisticsCo-AuthorSimilar Experts

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The NF1 Tumor Suppressor Regulates PD-L1 and Immune Evasion in Melanoma

Diana Berry,Dan Moldoveanu,Shivshankari Rajkumar,Mathieu Lajoie, Tiffany Lin, Daméhan Tchelougou, Samridhi Sakthivel,Itai Sharon, Antoine Bernard,Sandy Pelletier, Yael Ripstein,Alan Spatz,Wilson H Miller, Rahima Jamal,Réjean Lapointe,Anne-Marie Mes-Masson,Kevin Petrecca, Ari-Nareg Meguerditchian,Keith Richardson,Beatrice Wang,May Chergui,Marie-Christine Guiot,Kevin Watters,John Stagg,T Martin Schmeing,Francis Rodier,Simon Turcotte,Catalin Mihalcioiu,Sarkis Meterissian,Ian R Watson

Cell reports（2025）

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Spatially Mapping the Single-Cell Immune Landscapes of Melanoma Brain Metastases Using Imaging Mass Cytometry

Jamie Magrill, Sarah Allard-Puscas, Claris Gu,LeeAnn Ramsay,Mathieu Lajoie,Elham Karimi,Sarah M. Maritan,Matthew Dankner,Morteza Rezanejad,Dongmei Zuo, Yuhong Wei,Kevin Petrecca,Marie-christine Guiot,Bertrand Routy,Peter M. Siegel,Daniela Quail,Logan Walsh,Catalin Liviu Dragos Mihalcioiu,John Stagg,Ian Watson

JOURNAL OF CLINICAL ONCOLOGYno. 16 (2024)

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Mapping the Single Cell Spatial Immune Landscapes of the Melanoma Microenvironment

Jamie Magrill,Dan Moldoveanu, Jiayao Gu,Mathieu Lajoie,Ian R Watson

Clinical & Experimental Metastasis（2024）

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Supplementary Figure S1 from Mutations in the IFNγ-JAK-STAT Pathway Causing Resistance to Immune Checkpoint Inhibitors in Melanoma Increase Sensitivity to Oncolytic Virus Treatment

Tan-Trieu Nguyen,LeeAnn Ramsay,Mozhdeh Ahanfeshar-Adams,Mathieu Lajoie,Dirk Schadendorf, Tommy Alain,Ian R. Watson

openalex（2023）

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Supplementary Figure S5 from Mutations in the IFNγ-JAK-STAT Pathway Causing Resistance to Immune Checkpoint Inhibitors in Melanoma Increase Sensitivity to Oncolytic Virus Treatment

Tan-Trieu Nguyen,LeeAnn Ramsay,Mozhdeh Ahanfeshar-Adams,Mathieu Lajoie,Dirk Schadendorf,Tommy Alain,Ian R. Watson

openalex（2023）

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A Pilot Study of the Neoadjuvant Use of Vemurafenib Plus Cobimetinib in Patients with BRAF-mutant Melanoma with Palpable Lymph Node Metastases: Survival Results

Teresa M. Petrella,Catalin Liviu Dragos Mihalcioiu,Carolyn Nessim,Alan Spatz,Ian Watson,Frances Catriona Wright

JOURNAL OF CLINICAL ONCOLOGY（2023）

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Supplementary Table S2 from Mutations in the IFNγ-JAK-STAT Pathway Causing Resistance to Immune Checkpoint Inhibitors in Melanoma Increase Sensitivity to Oncolytic Virus Treatment

Tan-Trieu Nguyen,LeeAnn Ramsay,Mozhdeh Ahanfeshar-Adams,Mathieu Lajoie,Dirk Schadendorf, Tommy Alain,Ian R. Watson

openalex（2023）

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Associate Professor

Papers共 87 篇Author StatisticsCo-AuthorSimilar Experts