His research interests include the development of bioanalytical mass spectrometry methods for the structural characterization of proteins and their application for proteomics and disease biomarkers. He is also interested in the development and application of native mass spectrometry and top-down mass spectrometry for the study of protein complexes and their interactions with other binding partners and ligands. At UCLA, Dr. Loo teaches a course for undergraduate students on Chemical Instrumentation and a graduate level course on Proteomics and Mass Spectrometry.
He is an author of over 300 scientific publications. He has been on the Editorial Boards of Bioconjugate Chemistry, Analytical Chemistry, and Chemical & Engineering News, and Rapid Communications in Mass Spectrometry, and currently he serves on the Editorial Advisory Board for Clinical Proteomics and the International Journal of Mass Spectrometry. He is the Editor-in-Chief for the Journal of the American Society for Mass Spectrometry. In 2000-2002, he served on the Board of Directors for the American Society for Mass Spectrometry.