Much of Khurgin’s work lies at the intersection of optics and solid-state electronics. He has focused on an array of topics during his career, including the optics of semiconductor nanostructures, nonlinear optical devices, lasers, optical communications, microwave photonics, and condensed matter physics. His most recent work involves mid-infrared optical frequency combs, metamaterials, optical refrigeration of solids, and phonon engineering for high-frequency transistors, to name a few.