Janine Powers - Nurix Therapeutics | 人才画像

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论文共 23 篇作者统计合作学者相似作者

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Kinase-impaired BTK Mutations Are Susceptible to Clinical-Stage BTK and IKZF1/3 Degrader NX-2127

Skye Montoya,Jessie Bourcier,Mark Noviski, Hao Lu,Meghan C. Thompson,Alexandra Chirino,Jacob Jahn,Anya K. Sondhi, Stefan Gajewski,Ying Siow (May) Tan,Stephanie Yung,Aleksandra Urban,Eric Wang,Cuijuan Han,Xiaoli Mi,Won Jun Kim,Quinlan Sievers,Paul Auger,Hugo Bousquet,Nivetha Brathaban,Brandon Bravo,Melissa Gessner, Cristiana Guiducci,James N. Iuliano, Tim Kane,Ratul Mukerji, Panga Jaipal Reddy,Janine Powers, Mateo Sanchez Garcia de los Rios,Jordan Ye,Carla Barrientos Risso,Daniel Tsai,Gabriel Pardo,Ryan Q. Notti,Alejandro Pardo,Maurizio Affer,Vindhya Nawaratne,Tulasigeri M. Totiger,Camila Pena-Velasquez,Joanna M. Rhodes,Andrew D. Zelenetz,Alvaro Alencar,Lindsey E. Roeker,Sanjoy Mehta,Ralph Garippa,Adam Linley,Rajesh Kumar Soni,Sigrid S. Skanland, Robert J. Brown,Anthony R. Mato,Gwenn M. Hansen,Omar Abdel-Wahab,Justin Taylor

Scienceno. 6682 (2024)

引用24浏览0WOSSCIENCE引用

Discovery and Preclinical Pharmacology of NX-2127, an Orally Bioavailable Degrader of Bruton's Tyrosine Kinase with Immunomodulatory Activity for the Treatment of Patients with B Cell Malignancies

Daniel W. Robbins,Mark A. Noviski,Ying Siow Tan,Zef A. Konst,Aileen Kelly,Paul Auger,Nivetha Brathaban, Robert Cass, Ming Liang Chan,Ganesh Cherala,Matthew C. Clifton, Stefan Gajewski,Timothy G. Ingallinera,Dane Karr,Daisuke Kato, Jun Ma,Jenny McKinnell,Joel McIntosh,Jeff Mihalic, Brent Murphy, Jaipal Reddy Panga,Ge Peng,Janine Powers,Luz Perez,Ryan Rountree,Austin Tenn-McClellan,Arthur T. Sands,Dahlia R. Weiss,Jeffrey Wu,Jordan Ye, Cristiana Guiducci,Gwenn Hansen,Frederick Cohen

Journal of Medicinal Chemistryno. 4 (2024): 2321-2336

引用15浏览0WOS引用

NX-2127 and NX-5948, two clinical stage cereblon-recruiting BTK degraders, facilitate T-cell functionality in CLL

Tiana Huynh,Sonia Rodriguez-Rodriguez,Carly Roleder,Janine Powers,Alexey Danilov

LEUKEMIA & LYMPHOMA (2023): S181-S182

引用0浏览0引用

Initial clinical characterization of novel proximal biomarkers for nx-1607, a first-inclass oral cbl-b inhibitor, in patients with advanced malignancies

Sarah Whelan,Christopher Karim,Jordan Ye,Timothy Ingallinera,Ganesh Cherala,Katherine Jameson,Anja Williams,Adam Sharp,Matthew Krebs,Simon Pacey,Sarah Blagden,Ruth Plummer,Daniel Hochhauser,Jeff Evans,Johann De Bono,Janine Powers

Regular and Young Investigator Award Abstracts (2022): A809-A809

引用0浏览0引用

Concurrent Degradation of BTK and IMiD Neosubstrates by NX-2127 Enhances Multiple Mechanisms of Tumor Killing

Mark A. Noviski, Jun Ma,Ernestine Lee,Nivetha Brathaban,May Tan,Luz Perez,Daniel W. Robbins,Austin Tenn-McClellan,Janine Powers,Gwenn Hansen,Cristiana Guiducci,Ryan Rountree

CANCER RESEARCH（2022）

引用1浏览0引用

777 Initial Clinical Characterization of Novel Proximal Biomarkers for NX-1607, a First-in-class Oral CBL-B Inhibitor, in Patients with Advanced Malignancies

Sarah Whelan,Christopher Karim,Jordan Ye,Timothy Ingallinera,Ganesh Cherala,Katherine Jameson,Anja Williams,Adam Sharp,Matthew Krebs,Simon Pacey,Sarah P. Blagden,Ruth Plummer,Daniel Hochhauser,JEFF EVANS,Johann S. de Bono,Janine Powers

Regular and Young Investigator Award Abstracts (2022)

引用0浏览0引用

98 NX-0255, a Small Molecule CBL-B Inhibitor, Expands and Enhances Tumor Infiltrating Lymphocytes (TIL) for Use in Adoptive Cancer Immunotherapy

Sarah Whelan,Jennifa Gosling, Monisha Mani,Frederick Cohen,Austin Tenn-McClellan,Janine Powers,Gwenn Hansen,Michael Lotze,Arthur Sands

Regular and Young Investigator Award Abstracts（2021）

引用4浏览0引用

Phase I Escalation And Expansion Study Of Bemarituzumab (Fpa144) In Patients With Advanced Solid Tumors And Fgfr2b-Selected Gastroesophageal Adenocarcinoma (Vol 38, Pg 2418, 2020)

Daniel V. T. Catenacci,Drew Rasco,Jeeyun Lee,Sun Young Rha,Keun-Wook Lee,Yung Jue Bang,Johanna Bendell,Peter Enzinger,Neyssa Marina,Hong Xiang,Wei Deng,Janine Powers,Zev A. Wainberg

JOURNAL OF CLINICAL ONCOLOGY（2021）

引用0浏览0引用

Preclinical Characterization of Bemarituzumab, an Anti-Fgfr2b Antibody for the Treatment of Cancer

Hong Xiang, Abigael G. Chan,Ago Ahene,David I. Bellovin,Rong Deng,Amy W. Hsu, Ursula Jeffry,Servando Palencia,Janine Powers,James Zanghi,Helen Collins

mAbs（2021）

引用17浏览0WOS引用

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