基本信息
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Bio
In addition to my work as a Research Assistant Professor of Chemistry and Biochemistry at the University of Toledo, I am also the founder and Chief Scientific Officer of Oceanside Bioscience, LLC., located in West Haven, CT, USA.
My organization works as a CRO for pharma, biotech and academic drug discovery and development projects. We primarily work with the University of Toledo Instrumentation Center and the University of Michigan Life Sciences Institutes to conduct cutting edge structural analysis, SBDD and biophysics/ analytical chemistry to identify, characterize and deliver NCEs and NBEs to our clients.
Organizational Highlights:
· Successfully completed gene to structure projects for multiple clients. Conducted and/or supervised biophysical and biochemical assays to confirm ligand or PPI interaction with drug targets. Used computational biology to identify novel targets, confirm MOA.
· Generated high resolution, ligand-bound structures for multiple clients and assisted in the subsequent cycles of structure-guided drug design. Our scientists can work remotely, in-house and/or at the client site depending on the clients needs.
· Crystallized and structurally characterized (X-ray, PXRD, DSC, IR) dozens of small molecule compounds for the development project of a NYSE listed pharma client. Cross-validated drug polymorphs and co-authored a patent on a NCE that recently advanced to Phase III clinical trials.
Research Interests
Papers共 47 篇Author StatisticsCo-AuthorSimilar Experts
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Acta Crystallographica Section F Structural Biology Communicationsno. 4 (2019): 290-298
Mark E. Schnute,Stephen E. Benoit,Ingrid P. Buchler,Nicole Caspers,Margaret L. Grapperhaus,Seungil Han,Rajeev Hotchandani,Nelson Huang,Robert O. Hughes,Brian M. Juba,Kyung-Hee Kim,Erica Liu,Erin McCarthy,Dean Messing,Joy S. Miyashiro,Shashi Mohan,Thomas N. O'Connel,Jeffrey F. Ohren,Mihir D. Parikh,Michelle Schmidt,Shaun R. Selness,John R. Spriner,Venkataraman Thanabal,John I. Trujillo,Daniel P. Walker,Zhao-Kui Wan,Jane M. Withka,Arthur J. Wittwer,Nancy L. Wood,Li Xing,Christoph W. Zapf,John Douhan
Mark Schnute,John Springer,Shaun Selness,Robert Hughes,Jeff Ohren,Nicole Caspers,Seungil Han,Nelson Huang,Kieran Geoghegan,Li Xing,Margaret Grapperhaus, Thomas Owen,Michelle Schmidt,Balekudru Devadas,Susan Hockerman,D. Joseph Rogier,Christoph Zapf,Rajeev Hotchandani,Yuchuan Wu,Ingrid Buchler,Kyung-Hee Kim,Adrian Huang,Eva Chenail,Eddine Saiah,Zhao-Kui Wan,John Trujillo,Mihir Parikh,Arthur Wittwer,Evelyn Li,Erica Liu,Erin Mccarthy,Joy Miyashiro,Shashi Mohan,Nancy Wood,Jason Edmonds,Wenyan Miao,Nilufer Seth,David Beidler,Pratap Singh,Dean Messing,Sarah Soucy,Christopher Wrocklage, Tatyana Andrey,Andrew Rankin,Martin Hegen, Cheryl Nutter,John Douhan,Kyri Dunussi-Joannopoulos,Suvit Thaisrivongs
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Scot Mente,Eric Arnold,Todd Butler,Subramanyam Chakrapani,Ramalakshmi Chandrasekaran, Kevin Cherry,Ken DiRico,Angela Doran,Katherine Fisher,Paul Galatsis,Michael Green,Matthew Hayward,John Humphrey,John Knafels,Jianke Li,Shenping Liu,Michael Marconi,Scott McDonald,Jeff Ohren,Vanessa Paradis,Blossom Sneed,Kevin Walton,Travis Wager
JOURNAL OF MEDICINAL CHEMISTRYno. 17 (2013): 6819-6828
Travis T. Wager,Michael Marconi,Kevin Walton,Stefan Steyn,Cheng Chang,Angela Doran, Jenifer Bradley,Ramalakshmi Chandrasekaran,David Gebhard,Matthew Griffor,Jianke Li, Wayne Mcdonald,Scot Mente,Vanessa Paradis, Subbu Subramanyam,Terri Swanson,Todd Wisialowski,William Angus,Michael Green,Todd Butler,Paul Galatsis,John Knafels,Jeffrey Ohren,Kenneth Dirico,George Demarco
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Noel A. Powell,Jennifer K. Hoffman,Fred L. Ciske,Jeffrey T. Kohrt,Sangita M. Baxi, Yun-Wen Peng, Min Zhong,Cornel Catana,Jeff Ohren,Lisa A. Perrin,Jeremy J. Edmunds
Agustin Casimiro-Garcia,Robert P. Schaum,Declan Flynn,Christopher F. Bigge,Gary Bolton,Jing Chen, Lucinda Cohen,Jo Ann Davis,Danette A. Dudley,Jeremy J. Edmunds,Teresa Ellis,Noe Erasga,Nadia Esmaeil,Ronald J. Heemstra,Mehran Jalaie,Chitase Lee,Jeffrey F. Ohren,Robert Ostroski, Hud L. Risley,Meera Tugnait
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY (2012)
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Author Statistics
#Papers: 47
#Citation: 1958
H-Index: 23
G-Index: 34
Sociability: 6
Diversity: 2
Activity: 0
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