Jiekun Yang - Department of Psychiatry and Neurobehavioral Sciences, University of Virginia

基本信息

Career Trajectory

Bio

Jiekun Yang currently works at the Department of Biochemistry and Molecular Genetics, University of Virginia. Jiekun does research in Bioinformatics and Cancer Research. Their most recent publication is 'CRISPR knockout screening identifies combinatorial drug targets in pancreatic cancer and models cellular drug response'.

Research Interests

Papers共 30 篇Author StatisticsCo-AuthorSimilar Experts

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Antigen Presenting Cells in Cancer Immunity and Mediation of Immune Checkpoint Blockade

Cassia Wang,Lee Chen,Doris Fu,Wendi Liu,Anusha Puri,Manolis Kellis,Jiekun Yang

Clinical & Experimental Metastasispp.1-17, (2024)

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Depletion of Lamins B1 and B2 Promotes Chromatin Mobility and Induces Differential Gene Expression by a Mesoscale-Motion-dependent Mechanism

Emily M. Pujadas Liwag,Xiaolong Wei,Nicolas Acosta,Lucas M. Carter,Jiekun Yang,Luay M. Almassalha,Surbhi Jain,Ali Daneshkhah,Suhas S. P. Rao,Fidan Seker-Polat,Kyle L. MacQuarrie, Joe Ibarra,Vasundhara Agrawal,Erez Lieberman Aiden,Masato T. Kanemaki,Vadim Backman,Mazhar Adli

GENOME BIOLOGYno. 1 (2024)

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Disrupting CD38-driven T Cell Dysfunction Restores Sensitivity to Cancer Immunotherapy

Or-Yam Revach,Angelina M Cicerchia,Ofir Shorer,Boryana Petrova,Seth Anderson, Joshua Park,Lee Chen,Arnav Mehta,Samuel J Wright, Niamh McNamee,Aya Tal-Mason,Giulia Cattaneo,Payal Tiwari,Hongyan Xie,Johanna M Sweere,Li-Chun Cheng,Natalia Sigal, Elizabeth Enrico, Marisa Miljkovic, Shane A Evans,Ngan Nguyen, Mark E Whidden,Ramji Srinivasan,Matthew H Spitzer,Yi Sun,Tatyana Sharova,Aleigha R Lawless,William A Michaud,Martin Q Rasmussen,Jacy Fang, Claire A Palin,Feng Chen,Xinhui Wang,Cristina R Ferrone,Donald P Lawrence,Ryan J Sullivan,David Liu,Uma M Sachdeva,Debattama R Sen,Keith T Flaherty,Robert T Manguso,Lloyd Bod,Manolis Kellis,Genevieve M Boland,Keren Yizhak,Jiekun Yang,Naama Kanarek,Moshe Sade-Feldman,Nir Hacohen,Russell W Jenkins

bioRxiv the preprint server for biology (2024)

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Stratified Analysis Identifies HIF-2α As a Therapeutic Target for Highly Immune-Infiltrated Melanomas

Amy Y Huang,Kelly P Burke, Ryan Porter, Lynn Meiger, Peter Fatouros,Jiekun Yang,Emily Robitschek,Natalie Vokes,Cora Ricker, Valeria Rosado,Giuseppe Tarantino,Jiajia Chen, Tyler J Aprati, Marc C Glettig, Yiwen He,Cassia Wang,Doris Fu,Li-Lun Ho,Kyriakitsa Galani,Gordon J Freeman,Elizabeth I Buchbinder,F Stephen Hodi,Manolis Kellis,Genevieve M Boland,Arlene H Sharpe,David Liu

bioRxiv the preprint server for biology (2024)

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Mature and Migratory Dendritic Cells Promote Immune Infiltration and Response to Anti-Pd-1 Checkpoint Blockade in Metastatic Melanoma

Jiekun Yang,Cassia Wang,Doris Fu,Li-Lun Ho,Kyriakitsa Galani,Lee Chen,Dennie T Frederick,Liang He,Amy Y. Huang,Emily J. Robitschek, Sandeep K. Yadav, Wentao Deng, Rahul Tacke,Kelly P. Burke,Tatyana Sharova,Kunal Rai,David Liu,Genevieve M. Boland,Manolis Kellis

biorxiv（2024）

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Specific Oncogene Activation of the Cell of Origin in Mucosal Melanoma

bioRxiv the preprint server for biology (2024)

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Single-cell Transcriptomic and Epigenomic Landscapes of Innate and Adaptive Immune Cells in Metastatic Melanoma Treated with Immunotherapy

Jiekun Yang,Doris Fu,Kyriakitsa Galani,Li-Lun Ho,Emily J. Robitschek,Dennie T. Frederick, Sandeep K. Yadav, Wentao Deng,Anand K. Singh,Kelly P. Burke,Cassia Wang,Tatyana Sharova,David Liu,Kunal Rai,Genevieve M. Boland,Manolis Kellis

CANCER RESEARCHno. 7 (2023)

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Contextualized Networks Reveal Heterogeneous Transcriptomic Regulation in Tumors at Sample-Specific Resolution

Caleb N. Ellington,Benjamin J. Lengerich,Thomas B.K. Watkins,Jiekun Yang,Hanxi Xiao,Manolis Kellis,Eric P. Xing

biorxiv（2023）

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Multiomic Meta-Analysis of Differential Response to PD-1 and CTLA-4 Blockade in Metastatic Melanoma

Amy Y. Huang,Natalie Vokes,Cora Ricker,Tyler Aprati,Emily Robitschek,Jiekun Yang,Li-Lun Ho,Kyriakitsa Galani,Kelly P. Burke,Giuseppe Tarantino,Jiajia Chen,Arlene H. Sharpe,Eliezer M. Van Allen,Manolis Kellis,Genevieve M. Boland,David Liu

Cancer Researchno. 7_Supplement (2023): 3271-3271

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