Jimmy K. Eng spends much of his time researching PeptideAtlas, Proteome, Proteomics, Peptide sequence and Mass spectrometry. His research in PeptideAtlas intersects with topics in Sequence database, Trans-Proteomic Pipeline, XML, Software and Mass spectrometry data format. His studies in Proteome integrate themes in fields like Blood proteins, Computational biology and International Protein Index.

The concepts of his Proteomics study are interwoven with issues in DNA microarray and Molecular biology. The various areas that he examines in his Peptide sequence study include Amino acid, Tandem mass spectrometry and Bottom-up proteomics. His Mass spectrometry study integrates concerns from other disciplines, such as Biochemistry and Yeast.