Her research interests focus on understanding the mechanisms of stem cell fate regulation. Her lab particularly studies how stem cells sense environmental changes and determine their cell fate, and how niches develop and remodel the local environment during lung homeostasis, regeneration and the early stages of disease progression. Her group develops the state-of-the art technologies, including in vitro 3D human lung organoids and in vivo genetic labelling models, and employs computational analyses of single cell multi-omics and clonal biophysical modelling to map lineage hierarchy and stem-niche interactions at the single cell level.