Graduated in Dentistry from the University of São Paulo (1989), Master of Cellular and Structural Biology from State University of Campinas (1994) and Ph.D. in Chemistry from the University of Campinas (1998). He carried out postdoctoral fellow in Cell and Molecular Biology in the Chemical Institute at University of São Paulo (1999-2000). Currently work as Associate Professor at the Fluminense Federal University and Senior Scientist in Metrology and Quality at the National Institute of Metrology, Quality and Technology (Inmetro). He has experience in Bone Biology and Biomaterials, studying toxicity of biomaterials, cell-based therapy, tissue repair induced by growth factors and biomolecules, alternative methods to animal use, equivalent tissues development, search for new biomarkers of nanometric particules toxicity and nanostructured materials. He coordenates the Nanotox Network and a project to structure the National Network for Alternative Methods to Animal Use. Belongs to the National Council of Biotechnology (CNB), Consultive Council of Nanotecnology (CCNano/MCTI) and National Council for the Control of Animal Experimentation (CONCEA).