Keith Jones

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NXP800 Activates the Unfolded Protein Response, Altering AR and E2F Function to Impact Castration-Resistant Prostate Cancer Growth

Jonathan Welti,Denisa Bogdan,Ines Figueiredo,Ilsa Coleman, Juan Jiménez Vacas, Kate Liodaki, Franziska Weigl,Lorenzo Buroni, Wanting Zeng, Ilona Bernett,Claudia Bertan,Theodoros I Roumeliotis,Amandeep Bhamra,Jan Rekowski,Bora Gurel,Antje J Neeb,Jian Ning,Dapei Li,Veronica S Gil,Ruth Riisnaes,Susana Miranda, Mateus Crespo,Ana Ferreira,Nina Tunariu,Elisa Pasqua,Nicola Chessum,Matthew Cheeseman,Robert Te Poele,Marissa Powers,Suzanne Carreira,Jyoti Choudhary,Paul Clarke,Udai Banerji,Amanda Swain,Keith Jones,Wei Yuan,Paul Workman,Peter S Nelson,Johann S de Bono,Adam Sharp

Clinical cancer research an official journal of the American Association for Cancer Researchno. 6 (2025): 1109-1126

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Abstract PR-002: Activation of the Integrated Stress Response by NXP800, an Orally Available, Clinical-Stage, Investigational Agent in ARID1A-mutated, Platinum Resistant Ovarian Cancer

Marissa V. Powers, Swee Y. Swap,Robert te Poele,Eirini-Maria Lampraki,Toby Roe,Loredana Pellegrino,Maria Taskinen, Suzenne Eccles,Florence Raynaud,Matthew Cheeseman,Keith Jones,Paul A. Clarke,Paul Workman

Cancer Researchno. 5_Supplement_2 (2024)

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Using Acquired Resistance to Explore the Mechanism of Action of the Integrated Stress Response/gcn2 Activator NXP800 - A New Developmental Agent for Platinum-Resistant ARID1A Mutant Ovarian Cancer

Marissa V. Powers,Rachel Hodgson,Swee Y. Sharp,Toby Roe,K. Elizabeth Allen,Susan Campbell,Robert te Poele,Matthew Cheeseman,Keith Jones,Paul A. Clarke,Paul Workman

Cancer Research（2024）

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Discovery of ARID1A Loss As a Patient Biomarker for NXP800 - A Developmental Activator of the Integrated Stress Response (ISR) and Inhibitor of the HSF1 Pathway in Ovarian Cancer

Robert H. te Poele,Marissa Powers,Swee Sharp,Emmanuel de Billy,Maria Taskinen,Loredana Pellegrino,Sharon Gowan,Asadh Miah,Angela Hayes,Matthew Cheeseman,Keith Jones,Suzanne Eccles,Florence Raynaud,Paul Clarke,Paul Workman

Cancer Research（2024）

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Activation of the integrated stress response by NXP800, an orally available, clinical-stage, investigational agent in ARID1A-mutated, platinum resistant ovarian cancer

CANCER RESEARCHno. 5 (2024)

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Can I Get on the Plane? Stakeholder Perceptions of the Audit Report

Julia Ariel-Rohr,Joseph F. Brazel,Christine Gimbar,J. Gregory Jenkins,Keith Lamar Jones

crossref（2024）

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Activation of the integrated stress response by the developmental HSF1 pathway inhibitor NXP800

Marissa V. Powers,Swee Y. Sharp,Eirini-Maria Lampraki,Toby Roe,Loredana Pellegrino,Maria Taskinen,Robert Te Poele,Florence Raynaud,Suzanne Eccles,Matthew Cheeseman,Keith Jones,Paul A. Clarke,Paul Workman

CANCER RESEARCHno. 8 (2023)

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Abstract LB234: Activation of the Integrated Stress Response by the Developmental HSF1 Pathway Inhibitor NXP800

Marissa V. Powers,Swee Y. Sharp,Eirini-Maria Lampraki,Toby Roe,Loredana Pellegrino,Maria Taskinen,Robert te Poele,Florence Raynaud,Suzanne Eccles,Matthew Cheeseman,Keith Jones,Paul A. Clarke,Paul Workman

Cancer Research（2023）

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论文共 191 篇作者统计合作学者相似作者