Silva is prof. of biochemistry at the Federal Univ. of Rio de Janeiro (UFRJ), dir. of the Jiri Jonas Natl. Center of Nuclear Magnetic Resonance, and scientific dir. of the Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro. His research interest revolves around the understanding of biological recognition processes, especially how proteins correctly fold, misfold into species involved in neurodegenerative diseases, and form supramolecular complexes, such as virus particles. His work has opened new vistas for the use of pressure perturbations in the field of protein folding, structure and dynamics. He was nominated fellow of the John Simon Guggenheim Foundation, member of the Brazilian Acad. of Sciences. His honours include: Brazilian Order of Scientific Merit (Great-Cross), TWAS Prize in Biology and the FCW Prize in General Science from Fundação Conrado Wessel.