My principal research interest concerns brain-behavior relationships, both in
normals and in psychiatric populations. Methods of study include magnetic
resonance imaging (MRI) and spectroscopy (MRS), neuropsychological
investigations, psychopharmacological studies, cognitive-science paradigms,
and methodological inquiries. More specifically, topics of interest include
lesion and morphometric studies of discrete brain regions as they relate to
cognitive and other behavioral measures, pharmacodynamics, pharmacotherapy,
and psychometric investigations of reliability and validity. Gerontological
populations are of particular interest in relation to both normal and abnormal
aging, particularly dementia (e.g., Alzheimer's disease and vascular
dementia). Psychiatric disorders of particular interest include mood and
anxiety disorders.