Dr. Linfeng Huang’s research focuses on understanding RNA biology and developing RNA technology and RNA-based precision medicine. He made significant contributions to the RNA interference (RNAi) field including the discovery of the subunit structure of RNA polymerase V (Huang et al., Nature Structural & Molecular Biology, 2009) and the invention of the pro-siRNA (prokaryotic small interfering RNA) technology, which is the world’s first cell-based method for siRNA production (Huang et al., Nature Biotechnology, 2013; Huang & Lieberman, Nature Protocols, 2013). He also co-developed a technique for microRNA detection in live cells (Wang et al., Science Advances, 2020).