Luke D Tyson - Imperial College London

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Bio

Locum Consultant Hepatologist London North West University Healthcare NHS Trust. Gastroenterology and Hepatology Specialty Registrar (North West London) 2015-2023, CCT with Hepatology sub-specialty. Honorary Clinical Research Fellow and PhD student at Imperial College London. My research supervisors are Professor Mark Thursz and Professor Elaine Holmes. My research interests include alcohol-related liver disease, alcohol-related hepatitis, and the application of metabolomics to liver disease.

Research Interests

Papers共 31 篇Author StatisticsCo-AuthorSimilar Experts

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Longitudinal Paired Liver Biopsies and Transcriptome Profiling in Alcohol-Associated Hepatitis Reveal Dynamic Changes in Cellular Senescence

Daniel Rodrigo-Torres,Alastair M Kilpatrick,Sofia Ferreira-Gonzalez, Rhona E Aird, Stephen Rahul Atkinson,Victoria L Gadd,Tak Yung Man,Luke D Tyson, Gopal Krishna R Dhondalay,Nikhil Vergis,Gavin E Arteel, Mark R Thursz, Laura Martinez-Gili,Stuart J Forbes

Gut（2025）

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Lipidomics-based Plasma Signature of Alcohol-Related Hepatitis Linked to Short-Term Mortality

Florent Artru,Stephen Atkinson, Francesca Trovato,Luke D Tyson,Vishal C Patel,Nikhil Vergis, Noora Kano,Robert Goldin,Alberto Quaglia,Alexandros Pechlivanis, Phillip Morgan, Salma Mujib,Anna Cavazza,Ellen Jerome,Marc Zentar, Roosey Sheth, Maura Morrison,Evangelos Triantafyllou,Elaine Holmes,María Gómez-Romero, Mark J McPhail,Mark Thursz

JHEP reports innovation in hepatologyno. 6 (2025): 101367-101367

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OS-008-YI Cellular Senescence is Reduced Following Alcohol Cessation in Severe Alcohol-Associated Hepatitis

Daniel Rodrigo-Torres,Alastair M. Kilpatrick,Stephen R. Atkinson,Sofia Ferreira-Gonzalez,Luke D. Tyson,Nikhil Vergis,Mark R. Thursz,Laura Martinez-Gili,Stuart J. Forbes

Journal of Hepatology (2024): S14

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THU-326 Improvement in Alcohol-Associated Hepatitis is Characterized by Reduction of RNA Modification Processes

Alastair M. Kilpatrick,Daniel Rodrigo Torres,Stephen Atkinson,Luke D. Tyson,Nikhil Vergis,Mark R. Thursz,Laura Martinez-Gili,Stuart J. Forbes

Journal of Hepatology（2024）

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GENE ISOFORM TRANSCRIPT USAGE IS ASSOCIATED WITH HIGHER ALCOHOL-ASSOCIATED HEPATITIS SUSCEPTIBILITY IN FEMALES THAN MALES

Alastair Kilpatrick,Daniel Rodrigo-Torres,Luke Tyson,Stephen Atkinson,Nikhil Vergis,Mark Thursz,Laura Martinez-Gili,Stuart Forbes

HEPATOLOGY (2024)

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Serum Proteomic Analyses Reveal Elevated HGFand IL-8 in Patients with Alcohol-Related Hepatitis Compared to Decompensated Alcohol-Related Cirrhosis and Can Differentiate Patients with AH at Risk of Infection from Those at Risk of Acute Kidney Injury

Luke D. Tyson,Stephen R. Atkinson,Vishal C. Patel,Michael Allison,Andrew Austin,James W. Dear,Ewan H. Forrest, RobertW. Hunter,Tong Liu,Steven Masson,Mark J. W. McPhail, Joao Nunes,Paul Richardson,Stephen D. Ryder,Mark Wright,Elaine Holmes,Mark R. Thursz,Nikhil Vergis

JOURNAL OF HEPATOLOGY (2024): S145-S145

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SAT-274 Serum Proteomic Analyses Reveal Elevated HGFand IL-8 in Patients with Alcohol-Related Hepatitis Compared to Decompensated Alcohol-Related Cirrhosis and Can Differentiate Patients with AH at Risk of Infection from Those at Risk of Acute Kidney Injury

Luke D. Tyson,Stephen R. Atkinson,Vishal C. Patel,Michael Allison,Andrew Austin,James W. Dear,Ewan H. Forrest, RobertW. Hunter, Tong Liu,Steven Masson,Mark J.W. McPhail, Joao Nunes,Paul Richardson,Stephen D. Ryder,Mark Wright,Elaine Holmes,Mark R. Thursz,Nikhil Vergis

Journal of Hepatology (2024): S145

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TRANSCRIPTOMIC ANALYSIS IDENTIFIES SENESCENCE-RELATED MECHANISMS ASSOCIATED WITH DISEASE SEVERITY IN ALCOHOL-SSOCIATED HEPATITIS

Daniel Rodrigo-Torres,Alastair M. Kilpatrick,Stephen R. Atkinson,Sofia Ferreira-Gonzalez,Luke D. Tyson,Nikhil Vergis,Mark R. Thursz,Laura Martinez-Gili,Stuart J. Forbes

HEPATOLOGY (2023): S1664-S1664

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TRANSCRIPTOMIC ANALYSIS OF HIGH-GRADE FIBROSIS IN ALCOHOL-INDUCED LIVER DISEASE

Gopal Krishna R. Krishna Ramadas Dhondalay,Alastair M. Kilpatrick,Laura Martinez-Gili,Nikhil Vergis,Luke D. Tyson,Stephen R. Atkinson,Robert C. Glen,Timothy Md Ebbels,Ramon Bataller,Mark R. Thursz

HEPATOLOGY (2023): S1664-S1665

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