Nanoporous gold (npAu) is an active catalyst for a variety of catalytic applications in liquid and in gas phase (oxidation of CO, benzaldehyde, glucose, and methanol and many more). The finding that npAu can be highly active for oxidation reactions using molecular oxygen was a surprise within the field as gold based catalysts are usually comprised of oxide-supported nanoparticles in the range of a few nanometers – one order of magnitude smaller than the ligaments of npAu. The amount of Ag, for example, was already shown to be critical for the catalytic performance – pointing towards a bifunctional catalyst. How will the presence of other metals, such as Cu and Pt, impact the catalytic performance of npAu? We seek to get insight into options to control activity and selectivity as well as to improve long-term stability, using the oxidation of alcohols as a relevant reaction. As far as structural features are concerned, the pore and ligament sizes will not only influence the number of lowcoordinated sites but also mass transport within the material.