Mark Thursz - Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London;St Mary's Hospital

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Professor Thursz' research interests are focussed on the natural history of viral hepatitis and fatty liver disease and the factors which determine chronic infection and progressive liver disease. He has a special interest in the genetic determinants of disease outcomes using genetic association and genome wide scanning to identify causative variants.

Research Interests

Papers共 723 篇Author StatisticsCo-AuthorSimilar Experts

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Letter: Predictors of Corticosteroid Response in Alcohol-Related Hepatitis

Ewan Forrest,Richard Parker,Mark Thursz

Alimentary pharmacology & therapeuticsno. 9 (2025): 1569-1570

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An Expert Consensus Delphi Panel in Metabolic Dysfunction- and Alcohol-associated Liver Disease: Opportunities and Challenges in Clinical Practice

Luis Antonio Diaz,Veeral Ajmera,Juan Pablo Arab,Daniel Q Huang, Cynthia Hsu,Brian P Lee,Alexandre Louvet,Maja Thiele, Federica Tavaglione, Monica Tincopa,Elisa Pose, Leon A Adams,William Alazawi,Marco Arrese,Ramon Bataller,Ajay Duseja,Suthat Liangpunsakul, Michael R Lucey, Philippe Mathurin, Jessica Mellinger,Atsushi Nakajima,Vlad Ratziu,Nancy Reau,Mary E Rinella,Mark Thursz, Vincent Wai-Sun Wong,Patrick S Kamath,Rohit Loomba

Clinical gastroenterology and hepatology the official clinical practice journal of the American Gas...（2025）

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Mitochondrial Dysfunction Underlies Monocyte Immune Deficiency in Patients with Severe Alcohol-Related Hepatitis

Paul K. Middleton, Ricardo J. Aramayo, Alex Montoya, Pavel V. Shliaha, Simon Pope,Louise Fets,Nikhil Vergis,Mark R. Thursz, Helena M. Cochemé

biorxiv（2025）

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Spatial Lipidomics Reveals Sphingolipid Metabolism As Anti-Fibrotic Target in the Liver

Aleksandra Gruevska,Jack Leslie, Elena Perpiñán, Hannah Maude, Amy L Collins, Sophia Johnson, Laila Evangelista, Eleanor Sabey,Jeremy French,Steven White,John Moir, Stuart M Robinson, Wasfi Alrawashdeh, Rohan Thakkar,Roberta Forlano,Pinelopi Manousou,Robert Goldin,David Carling,Matthew Hoare,Mark Thursz,Derek A Mann, Inês Cebola, Joram M Posma, Niloufar Safinia,Fiona Oakley,Zoe Hall

Metabolism clinical and experimental（2025）

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Pathological Expansion of Gut Microbiome-Associated Enterococcus in Advanced Cirrhosis Corresponds with Multilevel Perturbations of the Gut-Liver-immune Axis

Matthew J Dalby,Raymond Kiu,Marilena Stamouli, Betsy Arefaine,Lex EX Leong, Jack Hales,Christine Bernsmeier,Arjuna Singanayagam,Sidsel Stoy,Maria-Emanuela Maxan,Merianne Mohamad,Ane Zamalloa, Mark Lewis,Royce P Vincent,Roger Williams,Lindsey A Edwards, Shilpa Chokshi,Mark Thursz,Naiara Beraza,Charalambos G Antoniades,Geraint B Rogers, Julia A Wendon,Kenneth D Bruce,Debbie L Shawcross,Mark JW McPhail,Lindsay J Hall,Vishal C Patel

medrxiv（2025）

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Larsucosterol for the Treatment of Alcohol-Associated Hepatitis

Mitchell Shiffman,Ben Da,Aparna Goel,Allison Kwong,Lance Stein,Christophe Moreno,Amanda Nicoll,Ashwini Mehta,Alexandre Louvet,Steven Flamm,Nikolaos Pyrsopoulos, Sanjaya Satapathy,Alexander Kuo,Daniel Ganger,Costica Aloman,Simone I Strasser,Edmund Tse, Mark W Russo,Don Rockey,Meagan Gray,Mack Mitchell,Mark Thursz,William Krebs,Deborah Scott,Christina Blevins, Dave Ellis, James Brown,Norman Sussman,WeiQi Lin

NEJM evidenceno. 2 (2025): EVIDoa2400243-EVIDoa2400243

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Lipidomics-based Plasma Signature of Alcohol-Related Hepatitis Linked to Short-Term Mortality

Florent Artru,Stephen Atkinson, Francesca Trovato,Luke D Tyson,Vishal C Patel,Nikhil Vergis, Noora Kano,Robert Goldin,Alberto Quaglia,Alexandros Pechlivanis, Phillip Morgan, Salma Mujib,Anna Cavazza,Ellen Jerome,Marc Zentar, Roosey Sheth, Maura Morrison,Evangelos Triantafyllou,Elaine Holmes,María Gómez-Romero, Mark J McPhail,Mark Thursz

JHEP reports innovation in hepatologyno. 6 (2025): 101367-101367

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Exploring the Immunomodulatory Potential of TLR7/8 Agonism in Decompensated Cirrhosis

Dimitrios Patseas, Roosey Sheth, Wing Yu Lee, Georgina Hagger,Eoin Mitchell,Francesca M. Trovato,Cathrin L. C. Gudd,Lucia A. Possamai,Mark R. Thursz,Mark J. W. McPhail,Evangelos Triantafyllou

JOURNAL OF HEPATOLOGY (2024): S181-S181

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Disruption of Gut Barrier Integrity and Host–microbiome Interactions Underlie MASLD Severity in Patients with Type-2 Diabetes Mellitus

R. Forlano,L. Martinez-Gili,P. Takis,J. Miguens-Blanco, T. Liu,E. Triantafyllou, C. Skinner,R. Loomba,M. Thursz,J. R. Marchesi,B. H. Mullish,P. Manousou

GUT MICROBESno. 1 (2024)

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