Her research is clinical and epidemiological, and she has led numerous Cochrane and other systematic reviews. Her research focuses on multidrug-resistant Gram-negative bacteria, hospital-acquired infections, and phase IV antibiotic trials. She also specializes in methodological study design, risk of bias assessment, meta-analysis and evidence grading. She has participated in previous WHO guideline development groups on iron supplementation (nutritional action group), the advisory committee on the clinical development pipeline of antibacterial treatments and the scientific group developing target product profiles for needed antibacterial treatments.