The research of Michael B. Wallace, M.D., focuses on advanced imaging systems for the detection and treatment of early cancers and pre-cancerous lesions of the gastrointestinal tract. These include methods to detect early cancer in Barrett's esophagus and subsequent imaging-guided endoscopic removal of the lesions. Similarly, his team has used advanced imaging systems to detect, characterize and remove advanced pre-cancerous lesions and early cancers from the colon through endoscopic resection. Together with basic optical physics researchers, Dr. Wallace is exploring methods to detect large field effects in the vicinity of pre-cancerous growths, which will improve screening and localization methods, such as for colonoscopy and pancreatic cancer detection.