Over the last 30 years the combination of more powerful computers combined with better theoretical and numerical methods has allowed us to routinely apply quantum mechanical methods to compute a vast range of properties of molecules and materials. For instance, to determine the most stable crystal structure for a particular combination of atoms even when this is not known experimentally. My group has played a leading role in this progress and continues to focus on the development of new tools and technologies which are designed to be accessible to all researchers.