I am a clinical trialist and translational research focused upon pancreatic and intestinal cancers. I have an extended focus on the rare tumor type of small bowel adenocarcinoma where we have molecularly characterized this cancer and developed model systems for study. I am principal investigator on a number of clinical trials investigating immune-checkpoint therapy in gastrointestinal malignancies. I have ongoing efforts to investigate the role of stromal modulation to enhance the activity of immune-checkpoint therapy.