Her main research interest is machine learning and data mining, in particular inductive logic programming and intelligent data analysis in medicine. She is coauthor of KARDIO: A Study in Deep and Qualitative Knowledge for Expert Systems, The MIT Press 1989, and Inductive Logic Programming: Techniques and Applications, Ellis Horwood 1994, and co-editor of Relational Data Mining, Springer 2001, Intelligent Data Analysis in Medicine and Pharmacology, Kluwer 1997. She was founder the Solomon European Network and acted as co-coordinator of the EU 5th Framework project Data Mining and Decision Support for Business Competitiveness: A European Virtual Enterprise (Sol-Eu-Net, IST-1999-11495, 2000-2003). She was coordinator of the European Scientific Network in Inductive Logic Programming ILPNET (1993-1996). She is member of editorial boards of Artificial Intelligence in Medicine AI Communications New Generation Computing Applied AI Machine Learning Journal and Data Mining and Knowledge Discovery. She was vice-president of ECCAI (1996-98), and is member of the International Machine Learning Society board (IMLS, 2001-2005), and Artificial Intelligence in Medicine board (AIME, 1999-2015).