Dr. Desai’s research interests include organizing large multi-center clinical trials to assess new cardiovascular technologies and health process evaluations using big-data and novel statistical approaches to improve quality of care for cardiac patients. Dr. Desai is the primary investigator of over 10 clinical trials currently ongoing at Penn, holds grants for database and registry development, and was recently awarded funding from the NHLBI to develop and direct a Clinical and Implementation Research Skills Program (CIRSP) for surgical trainees as part of a successful Penn U01 submission. Dr. Desai’s clinical focus is on advanced aortic surgery, both endovascular and open, percutaneous valve replacement, complex valve surgery, multiple arterial grafting, and arrhythmia surgery.