My principal research interest and focus has been in the evolution and epidemiology of virus infections, and interactions with their hosts. This has led to a variety of research investigations ranging from evolutionary studies of virus variability and recombination, molecular epidemiology and investigations of viral pathogenesis and interactions of virus with host cell defences. This has entailed use and development of a variety of molecular biology laboratory methods, and a wide range of genetic and bioinformatic analysis techniques that have been widely applied in a variety of virus groups.