I have spent much of my career working on elucidating mechanisms in the regulation of reproduction and have over 140 peer-reviewed publications, book chapters and editorials. At each stage I made contributions in the use of technologies to answer reproductive questions, including: remote telemetry of body-testis temperature differentials, MRI analysis of body composition and mammary gland, phage library and protein purification techniques to investigate reproductive proteins and proteomic and microarray techniques to study fetal development and endometriosis. Since the turn of the century, my research has focused on the effects of maternal factors, environmental exposures and endocrine disruption on fetal development and subsequent health in both human and animal models. My group is one of the few to work on the normal first and second trimester human fetus and uses maternal smoking, obesity and deprivation as a model to understand how adverse in-utero environment disturbs fetal development in our own species.